SCHEMBL10040451

SCHEMBL10040451

C=CC(=O)OCCCOc1ccc(C(=O)OC2CCC(OC)CC2)cc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTPN2 P17706 4/20 0.44
PTPN6 P29350 2/20 0.44
PTPN11 Q06124 2/20 0.44
THRB P10828 1/20 0.44
PTPN1 P18031 3/20 0.43
MAPT P10636 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.39
SCN1A P35498 1/20 0.39
SCN2A Q99250 1/20 0.39
SCN3A Q9NY46 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
GAA P10253 1/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12583926 0.97 PTPN2 (0.45) PTPN2PTPN6PTPN11THRBPTPN1
SCHEMBL10040448 0.97 PTPN2 (0.45) PTPN2PTPN6PTPN11THRBPTPN1
SCHEMBL26476871 0.91 PTPN2 (0.49) PTPN2PTPN6PTPN11THRBPTPN1
SCHEMBL25501073 0.91 PTPN2 (0.49) PTPN2PTPN6PTPN11THRBPTPN1
SCHEMBL25501078 0.91 PTPN2 (0.49) PTPN2PTPN6PTPN11THRBPTPN1
SCHEMBL18200265 0.90 PTPN2 (0.45) PTPN2PTPN6PTPN11THRBPTPN1
SCHEMBL12642655 0.88 PTPN2 (0.42) PTPN2PTPN6PTPN11THRBPTPN1
SCHEMBL13312817 0.88 PTPN2 (0.45) PTPN2PTPN6PTPN11THRBPTPN1
SCHEMBL19000204 0.87 THRB (0.45) PTPN2PTPN6PTPN11THRBPTPN1
SCHEMBL12671731 0.87 PTPN2 (0.47) PTPN2PTPN6PTPN11THRBPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11674082-B2 Polymerizable liquid crystal compound, liquid crystal composition for optical element, polymer, optically anisotropic body, and optical element for display device LG CHEM, LTD. 2023-06-13 US disclosed
US-11674082-B2 Polymerizable liquid crystal compound, liquid crystal composition for optical element, polymer, optically anisotropic body, and optical element for display device LG CHEM, LTD. 2023-06-13 US disclosed
US-11365354-B2 Polymerizable liquid crystal compound, liquid crystal composition for optical element, polymer, optically anisotropic body, and optical element for display device LG CHEM, LTD. 2022-06-21 US disclosed
EP-3789471-B1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION FOR OPTICAL ELEMENT, POLYMER, OPTICALLY ANISOTROPIC BODY, AND OPTICAL ELEMENT FOR DISPLAY DEVICE LG CHEMICAL LTD (KR) 2021-06-09 EP disclosed
US-20210155852-A1 Polymerizable Liquid Crystal Compound, Liquid Crystal Composition for Optical Element, Polymer, Optically Anisotropic Body, and Optical Element for Display Device LG CHEM, LTD. (KR) 2021-05-27 US disclosed
EP-3789471-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION FOR OPTICAL ELEMENT, POLYMER, OPTICALLY ANISOTROPIC BODY, AND OPTICAL ELEMENT FOR DISPLAY DEVICE LG CHEM, LTD. (KR) 2021-03-10 EP disclosed
US-20210062092-A1 Polymerizable Liquid Crystal Compound, Liquid Crystal Composition for Optical Element, Polymer, Optically Anisotropic Body, and Optical Element for Display Device LG CHEM, LTD. (KR) 2021-03-04 US disclosed
US-RE46426-E1 Birefringent polymer film with negative optical dispersion MERCK PATENT GMBH (DE) 2017-06-06 US disclosed
US-RE46426-E1 Birefringent polymer film with negative optical dispersion MERCK PATENT GMBH (DE) 2017-06-06 US disclosed
US-8697199-B2 Calamitic mesogenic compounds MERCK PATENT GMBH (DE) 2014-04-15 US disclosed
US-20100201920-A1 Calamitic Mesogenic Compounds MERCK PATENT GESELLSCHAFT (DE) 2010-08-12 US disclosed
US-20100110362-A1 Birefringent Polymer Film with Negative Optical Dispersion PARRI OWAIN LLYR 2010-05-06 US disclosed
US-20100110362-A1 Birefringent Polymer Film with Negative Optical Dispersion PARRI OWAIN LLYR 2010-05-06 US disclosed
US-20100072422-A1 Birefringent Layer with Negative Optical Dispersion MERCK PATENT GMBH (DE) 2010-03-25 US disclosed
US-20100072422-A1 Birefringent Layer with Negative Optical Dispersion MERCK PATENT GMBH (DE) 2010-03-25 US disclosed
WO-2010020312-A1 MESOGENIC COMPOUNDS COMPRISING DISCOTIC AND CALAMITIC GROUPS MERCK PATENT GMBH (DE) 2010-02-25 WO disclosed
WO-2009039937-A1 MESOGENIC DIMERS MERCK PATENT GMBH (DE) 2009-04-02 WO disclosed
WO-2009030332-A1 CALAMITIC MESOGENIC COMPOUNDS MERCK PATENT GMBH (DE) 2009-03-12 WO disclosed
WO-2009030352-A1 FLUORENE DERIVATIVES MERCK PATENT GMBH (DE) 2009-03-12 WO disclosed
WO-2008119427-A1 BIREFRINGENT POLYMER FILM WITH NEGATIVE OPTICAL DISPERSION MERCK PATENT GMBH (DE) 2008-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100110362-A1 Birefringent Polymer Film with Negative Optical Dispersion PUF60, LCP1, MAP1LC3C PTPN2 2653/4885PTPN6 2810/4885PTPN11 2630/4885
US-20100201920-A1 Calamitic Mesogenic Compounds CALD1, CALR, CALU PTPN2 1564/4885PTPN6 1016/4885PTPN11 386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.