Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 9/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Artemotil SCHEMBL1648554 | 1.00 | PTGES2 (0.76) | PTGES2LMNAHTTALDH1A1CYP3A4 | |
| Artemotil SCHEMBL16710281 | 1.00 | PTGES2 (0.76) | PTGES2LMNAHTTALDH1A1CYP3A4 | |
| Artemotil SCHEMBL17156474 | 1.00 | PTGES2 (0.76) | PTGES2LMNAHTTALDH1A1CYP3A4 | |
| Artemotil SCHEMBL16404848 | 1.00 | PTGES2 (0.76) | PTGES2LMNAHTTALDH1A1CYP3A4 | |
| Artemotil SCHEMBL341227 | 1.00 | PTGES2 (0.76) | PTGES2LMNAHTTALDH1A1CYP3A4 | |
| Artemotil SCHEMBL60335 | 1.00 | PTGES2 (0.76) | PTGES2LMNAHTTALDH1A1CYP3A4 | |
| Artemotil SCHEMBL18422062 | 1.00 | PTGES2 (0.76) | PTGES2LMNAHTTALDH1A1CYP3A4 | |
| Artemotil SCHEMBL60336 | 1.00 | PTGES2 (0.76) | PTGES2LMNAHTTALDH1A1CYP3A4 | |
| Artemotil SCHEMBL4539927 | 1.00 | PTGES2 (0.76) | PTGES2LMNAHTTALDH1A1CYP3A4 | |
| Artemotil SCHEMBL18950949 | 1.00 | PTGES2 (0.76) | PTGES2LMNAHTTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012042536-A2 | A PROCESS FOR PREPARATION OF ETHER DERIVATIVES OF DIHDROARTEMISININ | SEQUENT SCIENTIFIC LIMITED (IN) | 2012-04-05 | — | — | WO | disclosed |