Artemotil

Artemotil

SCHEMBL60335

CCO[C@H]1O[C@@H]2O[C@]3(C)CC[C@H]4[C@H](C)CC[C@@H]([C@H]1C)C24OO3

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGES2 Q9H7Z7 9/20 0.76
LMNA P02545 3/20 0.76
HTT P42858 3/20 0.65
ALDH1A1 P00352 3/20 0.65
CYP3A4 P08684 2/20 0.65
TP53 P04637 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
CYP1A2 P05177 2/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C19 P33261 1/20 0.51
HIF1A Q16665 1/20 0.51
NR1I2 O75469 1/20 0.51
CYP2B6 P20813 1/20 0.51
GAA P10253 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Artemotil SCHEMBL1648554 1.00 PTGES2 (0.76) PTGES2LMNAHTTALDH1A1CYP3A4
Artemotil SCHEMBL16710281 1.00 PTGES2 (0.76) PTGES2LMNAHTTALDH1A1CYP3A4
Artemotil SCHEMBL17156474 1.00 PTGES2 (0.76) PTGES2LMNAHTTALDH1A1CYP3A4
Artemotil SCHEMBL16404848 1.00 PTGES2 (0.76) PTGES2LMNAHTTALDH1A1CYP3A4
Artemotil SCHEMBL341227 1.00 PTGES2 (0.76) PTGES2LMNAHTTALDH1A1CYP3A4
Artemotil SCHEMBL18422062 1.00 PTGES2 (0.76) PTGES2LMNAHTTALDH1A1CYP3A4
Artemotil SCHEMBL10041607 1.00 PTGES2 (0.76) PTGES2LMNAHTTALDH1A1CYP3A4
Artemotil SCHEMBL60336 1.00 PTGES2 (0.76) PTGES2LMNAHTTALDH1A1CYP3A4
Artemotil SCHEMBL4539927 1.00 PTGES2 (0.76) PTGES2LMNAHTTALDH1A1CYP3A4
Artemotil SCHEMBL18950949 1.00 PTGES2 (0.76) PTGES2LMNAHTTALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3232 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250375399-A1 LIQUID INJECTABLE COMPOSITION AMATERASU LIFESCIENCES LLP (IN) 2025-12-11 US claimed
US-12485116-B2 Pharmaceutical composition for preventing or treating epidemic RNA viral infectious disease SHIN POONG PHARMACEUTICAL CO., LTD. (KR) 2025-12-02 US claimed
EP-3625238-B1 NOVEL SPIRO-LACTAM COMPOUNDS, PROCESS AND USES THEREOF UNIV DE COIMBRA (PT) 2025-11-26 EP claimed
US-12448559-B1 Puddle job with delayed setting of resin via a polymerization reaction with an activator HALLIBURTON ENERGY SERVICES, INC. (US) 2025-10-21 US claimed
US-12433869-B2 Preventing and treating malaria Shine, Ian Basil (US) 2025-10-07 US claimed
US-12409153-B2 Liquid injectable composition AMATERASU LIFESCIENCES LLP (IN) 2025-09-09 US claimed
EP-4129290-B1 PHARMACEUTICAL COMPOSITION COMPRISING PYRONARIDINE OR A SALT THEREOF, ARTEMISININ OR A DERIVATIVE THEREOF OR A COMBINATION OF BOTH FOR PREVENTING OR TREATING A RESPIRATORY DISEASE CAUSED BY A CORONAVIRUS SHIN POONG PHARMACEUTICAL CO LTD (KR) 2025-07-09 EP claimed
WO-2025133260-A1 INHIBITORS OF PLASMODIA REMODELING ENZYMES UNIVERSITÄT REGENSBURG, IN VERTRETUNG DES FREISTAATES BAYERN (DE) 2025-06-26 WO claimed
EP-4574143-A1 INHIBITORS OF PLASMODIA REMODELING ENZYMES Universität Regensburg (DE) 2025-06-25 EP claimed
EP-3990434-B1 1,1'-[1,3-(5-METHOXY)PHENYLENEBIS(METHYLENE)]BIS[4,5-DIPHENYL-1H-IMIDAZOLE] AND SIMILAR COMPOUNDS FOR THE TREATMENT OF MALARIA UNIV NANYANG TECH (SG) 2025-06-25 EP claimed
CN-1065993-A The preparation method of synergistic antimalarial compound benzfluorenol MICROBIOLOGICAL EPIDEMIOLOGY I (CN) 1992-11-11 CN claimed
EP-0500823-A1 ANTIMALARIAL COMPOSITIONS. CIBA GEIGY AG (CH) 1992-09-02 EP claimed
WO-1992002217-A1 ANTIMALARIAL COMPOSITIONS CIBA-GEIGY AG (CH) 1992-02-20 WO claimed
EP-0464233-A1 Pharmaceutical combinations against malaria HOECHST AKTIENGESELLSCHAFT (DE) 1992-01-08 EP claimed
US-5057501-A Methods for treatment of papulosquamous and eczematous diseases DERMATOLOGIC RESEARCH CORPORATION (US) 1991-10-15 US claimed
US-5011951-A Synthesis of artemisininelactol derivatives WORLD HEALTH ORGANIZATION (CH) 1991-04-30 US claimed
CN-1041694-A The anti-malaria composition of quinidine, arteannuin and derivant thereof and Therapeutic Method HOECHST AG (DE) 1990-05-02 CN claimed
EP-0362810-A1 Antimalarial compositions using quinidine, artemisinine and its derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1990-04-11 EP claimed
EP-0330520-A1 Synthesis of artemisininelactol derivatives WORLD HEALTH ORGANISATION (CH) 1989-08-30 EP claimed
EP-0290959-A2 Drug mixture for prophylaxis and therapy of malaria HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-17 EP claimed