SCHEMBL1004201

SCHEMBL1004201

OC[C@H]1O[C@@H](Oc2cccc3ccccc23)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.70

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CD209 Q9NNX6 1/20 0.70
ATM Q13315 1/20 0.62
SLC28A3 Q9HAS3 2/20 0.57
EPHX2 P34913 1/20 0.56
SLC5A2 P31639 6/20 0.55
TYR P14679 2/20 0.54
HIF1A Q16665 1/20 0.53
SLC5A1 P13866 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL869516 1.00 CD209 (0.70) CD209ATMSLC28A3EPHX2SLC5A2
SCHEMBL3727695 1.00 CD209 (0.70) CD209ATMSLC28A3EPHX2SLC5A2
SCHEMBL1228083 1.00 CD209 (0.70) CD209ATMSLC28A3EPHX2SLC5A2
SCHEMBL4609196 1.00 CD209 (0.70) CD209ATMSLC28A3EPHX2SLC5A2
SCHEMBL14974652 1.00 CD209 (0.70) CD209ATMSLC28A3EPHX2SLC5A2
SCHEMBL23479818 1.00 CD209 (0.70) CD209ATMSLC28A3EPHX2SLC5A2
SCHEMBL3742958 1.00 CD209 (0.70) CD209ATMSLC28A3EPHX2SLC5A2
SCHEMBL8654258 1.00 CD209 (0.70) CD209ATMSLC28A3EPHX2SLC5A2
SCHEMBL3759094 0.99 CD209 (0.67) CD209ATMSLC28A3EPHX2SLC5A2
SCHEMBL3739971 0.99 CD209 (0.67) CD209ATMSLC28A3EPHX2SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2270157-A2 Bitter taste receptors Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke (DE) 2011-01-05 EP claimed
EP-2163623-A2 Bitter taste receptors Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke (DE) 2010-03-17 EP claimed
US-20060248602-A1 Bitter taste receptors DEUTSCHES INSTITUT FUR ERNAHRUNGSFORSCHUNG (DE) 2006-11-02 US claimed
EP-1543122-A2 BITTER TASTE RECEPTORS Deutsches Institut für Ernährungsforschung (DE) 2005-06-22 EP claimed
US-6764832-B2 COMPOSITION FOR USE IN THE DETECTION OF SHIGELLA IN SAMPLE R&F PRODUCTS, INC. 2004-07-20 US claimed
WO-2004029087-A2 BITTER TASTE RECEPTORS Deutsches Institut für Ernährungsforschung (DE) 2004-04-08 WO claimed
US-20030049718-A1 Plating media for the presumptive identification of the genus Shigella and the species Shigella sonnei and shigella boydii R&F PRODUCTS, INC. 2003-03-13 US claimed
CN-106255689-B Heteroaryl SYK Inhibitors 勃林格殷格翰国际有限公司 2019-09-17 CN disclosed
CN-110183440-A Heteroaryl SYK inhibitor 勃林格殷格翰国际有限公司 2019-08-30 CN disclosed
CN-106255689-A Heteroaryl syk inhibitors 勃林格殷格翰国际有限公司 2016-12-21 CN disclosed
CN-103724328-B Cyclic pyrimidin-4-the methane amide of inflammation, asthma and COPD is used for the treatment of as CCR2 receptor antagonist BOEHRINGER INGELHEIM INT (DE) 2015-10-14 CN disclosed
CN-102933579-B New ccr2 receptor antagonists and uses thereof BOEHRINGER INGELHEIM INT 2015-07-15 CN disclosed
CN-101970682-B Method for detecting and/or identifying clostridium difficile BIOMERIEUX SA 2015-05-13 CN disclosed
EP-1066405-A1 NOVEL CHROMOGENOUS SUBSTRATES FOR DETECTING BACTERIAL HYDROLASE BIO MERIEUX (FR) 2001-01-10 EP disclosed
WO-1999051767-A1 NOVEL CHROMOGENOUS SUBSTRATES FOR DETECTING BACTERIAL HYDROLASE BIO MERIEUX (FR) 1999-10-14 WO disclosed
US-5766267-A USING FIBER REACTIVE DYES HOECHST AKTIENGESELLSCHAFT (DE) 1998-06-16 US disclosed
EP-0745719-A2 Use of carbohydrate compounds as auxiliary agents in the dyeing or printing of fibrous materials HOECHST AKTIENGESELLSCHAFT (DE) 1996-12-04 EP disclosed
EP-0620939-A4 AUTOMATED MULTICOMPARTMENTAL CELL CULTURE SYSTEM. CORNELL RES FOUNDATION INC (US) 1996-05-29 EP disclosed
EP-0620939-A1 AUTOMATED MULTICOMPARTMENTAL CELL CULTURE SYSTEM CORNELL RESEARCH FOUNDATION, INC. (US) 1994-10-26 EP disclosed
WO-1993011498-A1 AUTOMATED MULTICOMPARTMENTAL CELL CULTURE SYSTEM CORNELL RESEARCH FOUNDATION, INC. (US) 1993-06-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060248602-A1 Bitter taste receptors TAS2R1, TAS2R30, TAS2R5 CD209 4615/4885ATM 1731/4885SLC28A3 1555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.