TAS2R5

Taste receptor type 2 member 5 · Q9NYW4 · TAS2R5 on Sugi Atlas →

192 patent compounds predicted against TAS2R5, 159 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Isoproterenol (SCHEMBL4165)	1.00	1/20
Isoproterenol (SCHEMBL4166)	1.00	1/20
Levisoprenaline (SCHEMBL250806)	1.00	1/20
Isoproterenol (SCHEMBL3253794)	1.00	1/20
Isoproterenol (SCHEMBL29386243)	1.00	1/20
Isoproterenol (SCHEMBL29519146)	1.00	1/20
Levisoprenaline (SCHEMBL29620666)	1.00	1/20
Isoproterenol (SCHEMBL1333049)	0.97	1/20
Isoproterenol (SCHEMBL5682030)	0.97	1/20
Isoproterenol (SCHEMBL6151626)	0.97	1/20
Isoproterenol (SCHEMBL3669257)	0.93	1/20
Isoproterenol (SCHEMBL28121226)	0.90	1/20
Isoproterenol (SCHEMBL2232971)	0.88	1/20
Isoproterenol (SCHEMBL28106224)	0.88	1/20
Isoproterenol (SCHEMBL28296538)	0.88	1/20
Isoproterenol (SCHEMBL41841)	0.85	1/20
Metaproterenol (SCHEMBL3841247)	0.85	1/20
Isoproterenol (SCHEMBL7268328)	0.85	1/20
Isoproterenol (SCHEMBL9237796)	0.85	1/20
Isoproterenol (SCHEMBL5682034)	0.82	1/20

Clinical trials — most relevant to TAS2R5 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Clinical Trial of Efficacy and Safety of Raphamin in the Treatment of Coronavirus Disease 2019 in Outpatients	PHASE3	COMPLETED
Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes	PHASE2	COMPLETED
Role of the Gut Sweet Taste Receptor in the Secretion of Satiation Peptides	PHASE1	COMPLETED
Sweet Taste Receptors and the Secretion of Glucagon-like Peptide-1 and Peptide YY	PHASE1	COMPLETED
Role of the Gut Sweet Taste Receptor in the Secretion of Glucagon-like Peptide-1 and Peptide YY	PHASE1	COMPLETED
Vegetables Intake and Polymorphism TAS2R38 Gene by Healthy Adults	nan	COMPLETED
TAS1R1, TAS1R3, TLR2, TLR4, CA6 Gene Polymorphism on Dental Caries	nan	COMPLETED
Allele-specific Expression of a Bitter Taste Receptor	nan	COMPLETED
NUTRACORE, Glycaemic Index and Appetite	nan	COMPLETED
Flavour Programming: Fruit and Vegetable Palatability	nan	COMPLETED
The Effect of Lactisole on the Responses to Glucose Solution	nan	UNKNOWN
Fructose and Glucose and TAS1R2 in Type 1 Diabetes	nan	COMPLETED
Sensory Study: Taste and Tongue Biology	nan	COMPLETED
Ibuprofen Inhibits Human Sweet Taste	nan	COMPLETED
Bitter Taste Receptors in Oropharynx Cancer	nan	UNKNOWN
Study of Taste Deficits	nan	COMPLETED
Genetic Variability in Taste Perception	nan	COMPLETED
A Study of the Function of Hormones Present In Taste Buds	nan	COMPLETED
Sucralose and Lactisole Additions to OGTT in Humans	nan	COMPLETED
Factors Affecting Salt Intake in Young Adults	nan	UNKNOWN
CD36 and Human Fat Taste Perception	nan	COMPLETED
Astringency and Oral Health	nan	COMPLETED
Adaptation Strategies for Coping With the Impact of Sensory Alterations on Eating Behavior in Children With Cancer: A Qualitative Study From the Perspective of Children and Parents	nan	NOT_YET_RECRUITING
Taste Preferences for Nutritive and Non Nutritive Sweeteners Among Children and Adults	nan	COMPLETED
Gustatory Dysfunction Among a Sample of Depressed Egyptian Adults Under Anti-depressants Therapy	nan	COMPLETED
Gustin Gene Polymorphism and 6-n-propylthiouracil (PROP) Taste	nan	COMPLETED
Impacts of Sugar-Sweetened Beverage on Body Weight	nan	COMPLETED
The Effect of Artificial Sweeteners on Blood Glucose Response	nan	WITHDRAWN
Sensitive Periods in Early Flavor Learning	nan	COMPLETED
The Obese Taste Bud Study	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a TAS2R5 binder may also engage these)

Protein	Name	Similarity
Q646A4	—	1.000	Q646A4 →
Q645Z1	—	1.000	Q645Z1 →
Q645U0	—	1.000	Q645U0 →
Q646D5	—	1.000	Q646D5 →
Q646E6	—	1.000	Q646E6 →
Q646B2	—	0.998	Q646B2 →
Q645U7	—	0.996	Q645U7 →
Q7TQA6	—	0.996	Q7TQA6 →
TAS2R38	Taste receptor type 2 member 38	0.996	landscape →
Q697L5	—	0.996	Q697L5 →
Q646A5	—	0.996	Q646A5 →
TAS2R60	Taste receptor type 2 member 60	0.995	landscape →
Q645U6	—	0.995	Q645U6 →
Q646C7	—	0.994	Q646C7 →
Q645Y4	—	0.994	Q645Y4 →
Q67ES3	—	0.994	Q67ES3 →
Q646D1	—	0.994	Q646D1 →
Q697L6	—	0.994	Q697L6 →
P59532	—	0.993	P59532 →
Q646E7	—	0.993	Q646E7 →
Q645U1	—	0.993	Q645U1 →
TAS2R41	Taste receptor type 2 member 41	0.993	landscape →
Q646D0	—	0.993	Q646D0 →
Q7TQB9	—	0.993	Q7TQB9 →
Q697L2	—	0.993	Q697L2 →
Q9JKU0	—	0.992	Q9JKU0 →
Q646G6	—	0.992	Q646G6 →
Q646C8	—	0.992	Q646C8 →
Q9JKT2	—	0.992	Q9JKT2 →
Q67ES7	—	0.992	Q67ES7 →