SCHEMBL1004243

SCHEMBL1004243

CC(=CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4277057 1.00 THRB (0.38) THRB
SCHEMBL532520 1.00 THRB (0.38) THRB
SCHEMBL532522 1.00 THRB (0.38) THRB
SCHEMBL4272193 1.00 THRB (0.38) THRB
SCHEMBL1004867 0.98 THRB (0.34) THRB
SCHEMBL17784178 0.94
SCHEMBL532859 0.92 THRB (0.31) THRB
SCHEMBL532861 0.92 THRB (0.31) THRB
SCHEMBL12987146 0.92 CD81 (0.30)
SCHEMBL712239 0.92 CD81 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9238715-B2 Polymerizable composition for ophthalmic and medical use and antimicrobial composition obtained by polymerizing the polymerizable composition NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-01-19 US disclosed
US-20140163133-A1 POLYMERIZABLE COMPOSITION FOR OPHTHALMIC AND MEDICAL USE AND ANTIMICROBIAL COMPOSITION OBTAINED BY POLYMERIZING THE POLYMERIZABLE COMPOSITION MENICON CO., LTD (JP) 2014-06-12 US disclosed
US-8662663-B2 Hybrid soft contact lens, and production method and hydration treatment method thereof MENICON CO., LTD. (JP) 2014-03-04 US disclosed
EP-2578244-A1 POLYMERIZABLE COMPOSITION FOR OPHTHALMIC AND MEDICAL USE AND ANTIBACTERIAL COMPOSITION OBTAINED BY POLYMERIZING SAME Nanyang Technological University (SG) 2013-04-10 EP disclosed
US-7989560-B2 Fluorine-containing polymer and resin composition CHISSO CORPORATION (JP) 2011-08-02 US disclosed
US-7868112-B2 Fluorine-containing polymer and resin composition CHISSO CORPORATION (JP) 2011-01-11 US disclosed
US-20100093951-A1 FLUORINE-CONTAINING POLYMER AND RESIN COMPOSITION JNC CORPORATION (JP) 2010-04-15 US disclosed
US-20100063222-A1 FLUORINE-CONTAINING POLYMER AND RESIN COMPOSITION CHISSO CORPORATION (JP) 2010-03-11 US disclosed
US-7615283-B2 Curable via ultraviolet radiation; for use on signage 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-11-10 US disclosed
US-20070286993-A1 FLUORO(METH)ACRYLATE POLYMER COMPOSITION SUITABLE FOR LOW INDEX LAYER OF ANTIREFLECTIVE FILM 3M INNOVATIVE PROPERTIES COMPANY 2007-12-13 US disclosed
US-7261844-B2 For effectively reducing a period of time for discoloring a contact lens from a colored state to an uncolored state MENICON CO., LTD. (JP) 2007-08-28 US disclosed
US-7037954-B2 Ocular lens material MENICON CO., LTD. (JP) 2006-05-02 US disclosed
US-20050243273-A1 Photochromic contact lens having excellent discoloring characteristic MENICON CO., LTD. (JP) 2005-11-03 US disclosed
US-6087010-A PROVIDES COMPOUNDS HAVING SUFFICIENTLY LOW REFRACTIVE INDEX, SUFFICIENTLY HIGH SURFACE HARDNESS, AND ADHESION NOF CORPORATION (JP) 2000-07-11 US disclosed
US-5519070-A FLUORINE, ALKOXY POLYSILOXANE COPOLYMERS FOR INTRAOCULAR LENSES MENICON CO., LTD. (JP) 1996-05-21 US disclosed