Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 15/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 15/20 | 0.43 |
| ▸ | GABRP | O00591 | 14/20 | 0.43 |
| ▸ | GABRD | O14764 | 14/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 14/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 14/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 14/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 14/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 14/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 14/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 14/20 | 0.43 |
| ▸ | GABRE | P78334 | 14/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 14/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 14/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 14/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 14/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818736 | 0.86 | POLB (0.39) | ADORA2AADORA1GABRA2GABRB2GABRP | |
| SCHEMBL4435963 | 0.83 | GABRP (0.65) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL16463019 | 0.83 | ADORA2A (0.41) | ADORA2AADORA1GABRA2GABRB2GABRP | |
| SCHEMBL1006043 | 0.83 | POLB (0.49) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL15527783 | 0.82 | ADORA2A (0.39) | ADORA2AADORA1GABRA2GABRB2GABRP | |
| SCHEMBL4428924 | 0.82 | ADORA2A (0.42) | ADORA2AADORA1GABRA2GABRB2GABRP | |
| SCHEMBL4427761 | 0.81 | GABRP (0.50) | ADORA2AADORA1GABRA2GABRB2GABRP | |
| SCHEMBL1005105 | 0.81 | GABRP (0.49) | ADORA2AADORA1GABRA2GABRB2GABRP | |
| SCHEMBL1008749 | 0.80 | POLB (0.43) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL13300321 | 0.79 | POLB (0.64) | GABRA2GABRB2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629273-B2 | Diazinylpyrazolyl compounds | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| EP-2499130-A1 | NOVEL DIAZINYLPYRAZOLYL COMPOUNDS | Bayer CropScience AG (DE) | 2012-09-19 | — | — | EP | disclosed |
| US-20110124660-A1 | Novel Diazinylpyrazolyl Compounds | BAYER CROPSCIENCE AG (DE) | 2011-05-26 | — | — | US | disclosed |
| WO-2011057984-A1 | NOVEL DIAZINYLPYRAZOLYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | WO | disclosed |
| EP-2125789-B1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-03-16 | — | — | EP | disclosed |
| EP-2275422-A1 | Pyrimidinylpyrazoles as insecticide and parasiticide agents | Bayer CropScience AG (DE) | 2011-01-19 | — | — | EP | disclosed |
| US-20100144672-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2010-06-10 | — | — | US | disclosed |
| US-20100144672-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2010-06-10 | — | — | US | disclosed |
| US-20100144672-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2010-06-10 | — | — | US | disclosed |
| EP-2125789-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | Bayer CropScience AG (DE) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008077483-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008077483-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | BAYER CROPSCIENCE AG (DE) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144672-A1 | PYRIMIDINYL PYRAZOLES AS INSECTICIDES AND PARASITICIDE ACTIVE AGENTS | PIR, ITPA, DDT | ADORA2A 2314/4885ADORA1 2093/4885GABRA2 1142/4885 |
| US-20110124660-A1 | Novel Diazinylpyrazolyl Compounds | DDT, PDHX, RECQL | ADORA2A 3167/4885ADORA1 2188/4885GABRA2 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.