SCHEMBL10042663

SCHEMBL10042663

c1cc(-n2c3ccccc3c3cc(-c4cccs4)ccc32)cc(-n2c3ccccc3c3cc(-c4cccs4)ccc32)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.43
▸ L3MBTL1 Q9Y468 2/20 0.43
▸ ATM Q13315 1/20 0.43
▸ HPGD P15428 3/20 0.41
▸ NR4A2 P43354 1/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ PLA2G1B P04054 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ ATG4B Q9Y4P1 1/20 0.41
▸ KCNH2 Q12809 1/20 0.41
▸ LTA4H P09960 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ ALOX5 P09917 2/20 0.37
▸ PGR P06401 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.36
▸ HTR1D P28221 1/20 0.36
▸ HTR1B P28222 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27970170 1.00 KDM4E (0.43) KDM4EL3MBTL1ATMHPGDNR4A2
SCHEMBL27959988 0.93 KDM4E (0.44) KDM4EL3MBTL1ATMHPGDNR4A2
SCHEMBL2269282 0.90 KDM4E (0.47) KDM4EL3MBTL1ATMHPGDMEN1
SCHEMBL27964962 0.88 KDM4E (0.46) KDM4EL3MBTL1ATMHPGDNR4A2
SCHEMBL15867537 0.87 HPGD (0.37) KDM4EL3MBTL1ATMHPGDNR4A2
SCHEMBL18352325 0.83 KDM4E (0.57) KDM4EL3MBTL1ATMHPGDMEN1
SCHEMBL15685606 0.81 KDM4E (0.41) KDM4EL3MBTL1ATMHPGDNR4A2
SCHEMBL18468317 0.81 KDM4E (0.55) KDM4EL3MBTL1ATMHPGDMEN1
SCHEMBL23341615 0.80 L3MBTL1 (0.53) KDM4EL3MBTL1ATMHPGDMEN1
SCHEMBL12113746 0.80 L3MBTL1 (0.53) KDM4EL3MBTL1ATMHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192847-B2 Organic electroluminescent device material, organic electroluminescent device, display and illuminating device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-06-05 — — US disclosed
US-8192847-B2 Organic electroluminescent device material, organic electroluminescent device, display and illuminating device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-06-05 — — US disclosed
US-20090167165-A1 ORGANIC ELECTROLUMINESCENT DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-07-02 — — US disclosed
US-20090167165-A1 ORGANIC ELECTROLUMINESCENT DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-07-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090167165-A1 ORGANIC ELECTROLUMINESCENT DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY AND ILLUMINATING DEVICE L1CAM, OR10J3, ICOSLG KDM4E 1687/4885L3MBTL1 191/4885ATM 3191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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