SCHEMBL10042838

SCHEMBL10042838

Cc1ccc(-c2ccc(N(C)c3cccc(C)c3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 4/20 0.47
HSD17B2 P37059 4/20 0.47
CSF1R P07333 5/20 0.42
EGFR P00533 4/20 0.42
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ACHE P22303 1/20 0.41
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
NSD2 O96028 1/20 0.40
CASP3 P42574 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
SIGMAR1 Q99720 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10042839 0.94 TSHR (0.46) HSD17B1HSD17B2CSF1REGFRTSHR
SCHEMBL10042856 0.91 HSD17B1 (0.44) HSD17B1HSD17B2CSF1REGFRTSHR
SCHEMBL13367611 0.91 HSD17B1 (0.50) HSD17B1HSD17B2CSF1REGFRTSHR
SCHEMBL10042848 0.89 HSD17B1 (0.45) HSD17B1HSD17B2CSF1REGFRTSHR
SCHEMBL16573914 0.89 HSD17B1 (0.40) HSD17B1HSD17B2CSF1REGFRTSHR
SCHEMBL12048248 0.89 CSF1R (0.42) HSD17B1HSD17B2CSF1REGFRTSHR
SCHEMBL14877955 0.88 HSD17B1 (0.42) HSD17B1HSD17B2TSHRALDH1A1ACHE
Methylamine SCHEMBL294733 0.87 HSD17B1 (0.48) HSD17B1HSD17B2CSF1REGFRTSHR
SCHEMBL12048276 0.87 HSD17B1 (0.44) HSD17B1HSD17B2CSF1REGFRTSHR
SCHEMBL10042837 0.87 CSF1R (0.41) HSD17B1HSD17B2CSF1REGFRTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9972802-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2018-05-15 US disclosed
US-9773993-B2 Electroluminescence element Konica Minolta, Inc. (JP) 2017-09-26 US disclosed
US-9640775-B2 Organic electroluminescence element Konica Minolta, Inc. (JP) 2017-05-02 US disclosed
US-20160336526-A1 ELECTROLUMINESCENCE ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-11-17 US disclosed
US-9257651-B2 Organic electroluminescence element and method for manufacturing organic electroluminescence element KONICA MINOLTA HOLDINGS, INC. (JP) 2016-02-09 US disclosed
US-20150076469-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-03-19 US disclosed
US-8980443-B2 Organic electroluminescent element KONICA MINOLTA HOLDINGS, INC. (JP) 2015-03-17 US disclosed
US-8759826-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2014-06-24 US disclosed
US-20130200360-A1 ORGANIC ELECTROLUMINESCENT ELEMENT KONICA MINOLTA , INC. (JP) 2013-08-08 US disclosed
US-20130087778-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND METHOD FOR MANUFACTURING ORGANIC ELECTROLUMINESCENCE ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2013-04-11 US disclosed
US-20120037889-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE AND ILLUMINATION DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2012-02-16 US disclosed
US-20120007072-A1 ORGANIC ELECTROLUMINESCENT ELEMENT MERCK PATENT GMBH (DE) 2012-01-12 US disclosed