SCHEMBL10042891

SCHEMBL10042891

CCCCc1ccc(N(c2ccc(N(c3ccccc3)c3ccccc3)cc2)c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CHRM2 P08172 1/20 0.52
HTR1A P08908 1/20 0.52
ADRA2A P08913 1/20 0.52
CHRM1 P11229 1/20 0.52
DRD1 P21728 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
ADRA1A P35348 1/20 0.52
OPRM1 P35372 1/20 0.52
DRD3 P35462 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HSD11B1 P28845 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
HSD17B10 Q99714 1/20 0.50
BCHE P06276 1/20 0.47
TRPV1 Q8NER1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12313748 1.00 KCNH2 (0.52) KCNH2CA1CA2CHRM2HTR1A
SCHEMBL13990681 1.00 KCNH2 (0.52) KCNH2CA1CA2CHRM2HTR1A
SCHEMBL987390 1.00 KCNH2 (0.52) KCNH2CA1CA2CHRM2HTR1A
SCHEMBL3375506 1.00 KCNH2 (0.52) KCNH2CA1CA2CHRM2HTR1A
SCHEMBL10358429 1.00 KCNH2 (0.52) KCNH2CA1CA2CHRM2HTR1A
SCHEMBL1170313 1.00 KCNH2 (0.52) KCNH2CA1CA2CHRM2HTR1A
SCHEMBL10042893 1.00 KCNH2 (0.52) KCNH2CA1CA2CHRM2HTR1A
SCHEMBL309398 0.94 RARB (0.54) KCNH2CA1CA2CHRM2HTR1A
SCHEMBL38667 0.94 RARB (0.54) KCNH2CA1CA2CHRM2HTR1A
SCHEMBL289833 0.94 RARB (0.54) KCNH2CA1CA2CHRM2HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120037889-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE AND ILLUMINATION DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2012-02-16 US disclosed