SCHEMBL309398

SCHEMBL309398

CCCCc1ccc(N(c2ccccc2)c2ccc(-c3ccc(-c4ccc(N(c5ccccc5)c5ccc(CCCC)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.54
HSD11B1 P28845 2/20 0.54
ALDH1A1 P00352 2/20 0.47
MEN1 O00255 1/20 0.47
RARA P10276 1/20 0.47
MAPT P10636 1/20 0.47
MTOR P42345 1/20 0.47
KMT2A Q03164 1/20 0.47
KCNH2 Q12809 2/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CHRM2 P08172 1/20 0.47
HTR1A P08908 1/20 0.47
ADRA2A P08913 1/20 0.47
CHRM1 P11229 1/20 0.47
DRD1 P21728 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
ADRA1A P35348 1/20 0.47
OPRM1 P35372 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL289833 1.00 RARB (0.54) RARBHSD11B1ALDH1A1MEN1RARA
SCHEMBL12533891 1.00 RARB (0.54) RARBHSD11B1ALDH1A1MEN1RARA
SCHEMBL38667 1.00 RARB (0.54) RARBHSD11B1ALDH1A1MEN1RARA
SCHEMBL13474962 1.00 RARB (0.54) RARBHSD11B1ALDH1A1MEN1RARA
SCHEMBL10042892 0.98 HSD11B1 (0.57) RARBHSD11B1ALDH1A1MEN1RARA
SCHEMBL11887113 0.96 HSD11B1 (0.58) RARBHSD11B1ALDH1A1MEN1RARA
SCHEMBL12386345 0.96 HSD11B1 (0.58) RARBHSD11B1ALDH1A1MEN1RARA
SCHEMBL10042894 0.96 HSD11B1 (0.58) RARBHSD11B1ALDH1A1MEN1RARA
SCHEMBL16234053 0.95 RARB (0.50) RARBHSD11B1ALDH1A1MEN1RARA
SCHEMBL16253925 0.95 RARB (0.56) RARBHSD11B1ALDH1A1MEN1RARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10281831-B2 Imaging members comprising capped structured organic film compositions XEROX CORPORATION (US) 2019-05-07 US disclosed
US-9921500-B2 Fluorinated structured organic film photoreceptor layers XEROX CORPORATION (US) 2018-03-20 US disclosed
US-20180004102-A1 METHOD FOR MANUFACTURING FLUORINATED STRUCUTURED ORGANIC PHOTORECEPTOR LAYERS XEROX CORPORATION 2018-01-04 US disclosed
US-20180004103-A1 FLUORINATED STRUCUTURED ORGANIC FILM LAYERS XEROX CORPORATION 2018-01-04 US disclosed
EP-3264183-A1 FLUORINATED STRUCUTURED ORGANIC FILM LAYER PHOTORECEPTOR LAYERS Xerox Corporation (US) 2018-01-03 EP disclosed
EP-3264182-A1 METHOD FOR MANUFACTURING FLUORINATED STRUCUTURED ORGANIC PHOTORECEPTOR LAYERS Xerox Corporation (US) 2018-01-03 EP disclosed
US-20170075238-A1 FLUORINATED STRUCTURED ORGANIC FILM PHOTORECEPTOR LAYERS XEROX CORPORATION (US) 2017-03-16 US disclosed
US-9567425-B2 Periodic structured organic films XEROX CORPORATION (US) 2017-02-14 US disclosed
US-20170022338-A1 PERIODIC STRUCTURED ORGANIC FILMS XEROX CORPORATION 2017-01-26 US disclosed
EP-2403657-B1 PROCESS FOR PREPARING STRUCTURED ORGANIC FILMS (SOFS) VIA A PRE-SOF XEROX CORP (US) 2016-12-28 EP disclosed
US-20110217642-A1 CHARGE TRANSPORT PARTICLES XEROX CORPORATION (US) 2011-09-08 US disclosed
WO-2010102038-A1 ELECTRONIC DEVICES COMPRISING STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-10 WO disclosed
US-20100227157-A1 COMPOSITE STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-09 US disclosed
US-20100228025-A1 STRUCTURED ORGANIC FILMS HAVING AN ADDED FUNCTIONALITY XEROX CORPORATION (US) 2010-09-09 US disclosed
US-20100227998-A1 STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-09 US disclosed
US-20100227081-A1 MIXED SOLVENT PROCESS FOR PREPARING STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-09 US disclosed
US-20100224867-A1 ELECTRONIC DEVICES COMPRISING STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-09 US disclosed
US-20100227071-A1 PROCESS FOR PREPARING STRUCTURED ORGANIC FILMS (SOFS) VIA A PRE-SOF XEROX CORPORATION (US) 2010-09-09 US disclosed
US-20100221648-A1 ZINC THIONE PHOTOCONDUCTORS XEROX CORPORATION (US) 2010-09-02 US disclosed
US-20100221648-A1 ZINC THIONE PHOTOCONDUCTORS XEROX CORPORATION (US) 2010-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100224867-A1 ELECTRONIC DEVICES COMPRISING STRUCTURED ORGANIC FILMS EPCAM, EPHA6, EED RARB 1405/4885HSD11B1 4746/4885ALDH1A1 866/4885
US-20100228025-A1 STRUCTURED ORGANIC FILMS HAVING AN ADDED FUNCTIONALITY VIM, PUF60, EPCAM RARB 1629/4885HSD11B1 4727/4885ALDH1A1 1258/4885
US-20100227998-A1 STRUCTURED ORGANIC FILMS VIM, PUF60, EPCAM RARB 1478/4885HSD11B1 4727/4885ALDH1A1 1213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.