SCHEMBL10044100

SCHEMBL10044100

CCCCC(=O)C(=O)NCCc1ccc(O)cc1

nearest known ligand 0.72

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PLAAT5 Q96KN8 12/20 0.72
PLAAT4 Q9UL19 12/20 0.72
PLAAT3 P53816 11/20 0.72
PLAAT2 Q9NWW9 11/20 0.72
KDM4E B2RXH2 2/20 0.57
F13A1 P00488 1/20 0.57
HSD17B10 Q99714 2/20 0.53
ABCG2 Q9UNQ0 1/20 0.51
TRPV1 Q8NER1 1/20 0.50
MEN1 O00255 1/20 0.50
MAPT P10636 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7197408 0.83 ESR1 (0.59) PLAAT5PLAAT4PLAAT3PLAAT2KDM4E
SCHEMBL8622037 0.83 ESR1 (0.59) PLAAT5PLAAT4PLAAT3PLAAT2KDM4E
SCHEMBL2723955 0.80 HSD17B10 (0.70) KDM4EF13A1HSD17B10TRPV1MEN1
SCHEMBL8337981 0.79 HSD17B10 (0.72) KDM4EHSD17B10TRPV1MEN1MAPT
SCHEMBL8660817 0.79 HSD17B10 (0.72) KDM4EHSD17B10TRPV1MEN1MAPT
SCHEMBL13804558 0.79 HSD17B10 (0.72) KDM4EHSD17B10TRPV1MEN1MAPT
SCHEMBL7195864 0.79 HSD17B10 (0.72) KDM4EHSD17B10TRPV1MEN1MAPT
SCHEMBL8587170 0.79 HSD17B10 (0.72) KDM4EHSD17B10TRPV1MEN1MAPT
SCHEMBL14773849 0.79 HSD17B10 (0.72) KDM4EHSD17B10TRPV1MEN1MAPT
SCHEMBL31746144 0.79 HSD17B10 (0.72) KDM4EHSD17B10TRPV1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015081390-A2 METHOD FOR CONTROLLING ANT COLONIES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2015-06-11 WO claimed
US-11767289-B2 Methods and compositions for pest control UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2023-09-26 US disclosed
US-11767289-B2 Methods and compositions for pest control UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2023-09-26 US disclosed
US-11767289-B2 Methods and compositions for pest control UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2023-09-26 US disclosed
US-20220234997-A1 Methods and Compositions for Pest Control THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2022-07-28 US disclosed
US-9950994-B2 Methods and compositions for pest control VMI FOUNDATION (US) 2018-04-24 US disclosed
US-9950994-B2 Methods and compositions for pest control VMI FOUNDATION (US) 2018-04-24 US disclosed
US-9950994-B2 Methods and compositions for pest control VMI FOUNDATION (US) 2018-04-24 US disclosed
US-20180009740-A1 Methods and Compositions for Pest Control THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2018-01-11 US disclosed
US-20180009740-A1 Methods and Compositions for Pest Control THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2018-01-11 US disclosed
WO-2015081390-A2 METHOD FOR CONTROLLING ANT COLONIES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2015-06-11 WO disclosed
US-20130289125-A1 Methods and Compositions for Pest Control THE VMI FOUNDATION 2013-10-31 US disclosed
US-20130289125-A1 Methods and Compositions for Pest Control THE VMI FOUNDATION 2013-10-31 US disclosed
US-20130289125-A1 Methods and Compositions for Pest Control THE VMI FOUNDATION 2013-10-31 US disclosed
WO-2012061624-A2 Methods and Compositions for Pest Control VMI FOUNDATION (US) 2012-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11767289-B2 Methods and compositions for pest control TYR, GLMN, SGMS2 PLAAT5 641/4885PLAAT4 1153/4885PLAAT3 2138/4885
US-20130289125-A1 Methods and Compositions for Pest Control TYR, GLMN, SGMS2 PLAAT5 641/4885PLAAT4 1153/4885PLAAT3 2138/4885
US-20180009740-A1 Methods and Compositions for Pest Control TYR, GLMN, SGMS2 PLAAT5 641/4885PLAAT4 1153/4885PLAAT3 2138/4885
US-20220234997-A1 Methods and Compositions for Pest Control TYR, GLMN, SGMS2 PLAAT5 641/4885PLAAT4 1153/4885PLAAT3 2138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.