SCHEMBL1004433

SCHEMBL1004433

CCCCCc1ccccc1C(N)=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.55
LMNA P02545 2/20 0.55
MEN1 O00255 1/20 0.55
NR1I2 O75469 1/20 0.55
CHRM2 P08172 1/20 0.55
ADRA2A P08913 1/20 0.55
MAPT P10636 1/20 0.55
OPRK1 P41145 1/20 0.55
HTR2B P41595 1/20 0.55
SLC6A3 Q01959 1/20 0.55
KMT2A Q03164 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
LIPG Q9Y5X9 1/20 0.51
BID P55957 3/20 0.47
MCL1 Q07820 3/20 0.47
BCL2L1 Q07817 2/20 0.47
BAK1 Q16611 2/20 0.47
KAT8 Q9H7Z6 2/20 0.47
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1002751 0.98 LMNA (0.58) CYP3A4LMNAMEN1NR1I2CHRM2
SCHEMBL31079007 0.98 LMNA (0.58) CYP3A4LMNAMEN1NR1I2CHRM2
SCHEMBL1003626 0.98 LMNA (0.58) CYP3A4LMNAMEN1NR1I2CHRM2
SCHEMBL1004461 0.98 LMNA (0.58) CYP3A4LMNAMEN1NR1I2CHRM2
SCHEMBL421013 0.98 LMNA (0.58) CYP3A4LMNAMEN1NR1I2CHRM2
SCHEMBL1004554 0.98 LMNA (0.58) CYP3A4LMNAMEN1NR1I2CHRM2
SCHEMBL1002777 0.98 LMNA (0.58) CYP3A4LMNAMEN1NR1I2CHRM2
SCHEMBL5566506 0.98 LMNA (0.58) CYP3A4LMNAMEN1NR1I2CHRM2
SCHEMBL1003944 0.98 LMNA (0.58) CYP3A4LMNAMEN1NR1I2CHRM2
SCHEMBL28193718 0.98 LMNA (0.58) CYP3A4LMNAMEN1NR1I2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4065549-B1 CANNABINOID DERIVATIVES CANOPY GROWTH CORP (CA) 2026-03-11 EP claimed
EP-4065549-A1 CANNABINOID DERIVATIVES Canopy Growth Corporation (CA) 2022-10-05 EP claimed
WO-2021102568-A1 CANNABINOID DERIVATIVES CANOPY GROWTH CORPORATION (CA) 2021-06-03 WO claimed
EP-3781142-A1 NOVEL [1.1.1] BICYCLO COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS Merck Sharp&Dohme Corp. (US) 2021-02-24 EP claimed
CN-112107684-A Methods and compositions for treating ARID2 or HSPA1A mediated diseases 中国科学院分子细胞科学卓越创新中心 2020-12-22 CN claimed
WO-2019204180-A1 NOVEL [1.1.1] BICYCLO COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS MERCK SHARP & DOHME CORP. (US) 2019-10-24 WO claimed
CN-108864038-A 3- amide groups-N- aryl benzamides class compound and preparation and application 浙江大学 2018-11-23 CN claimed
CN-102762557-B Triazolopyridine BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-10-07 CN claimed
CN-102762557-A Triazolopyridines BAYER SCHERING PHARMA AG 2012-10-31 CN claimed
EP-1888595-A2 SPIRO-OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2008-02-20 EP claimed
WO-2006110917-A2 SPIRO-OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2006-10-19 WO claimed
US-12415822-B2 Small molecule inhibitors selective for polo-like kinase protein UNIVERSITY OF SOUTH CAROLINA (US) 2025-09-16 US disclosed
US-20250188201-A1 CATALYST FOR PHOTOCATALYTIC POLYMERIZATION REACTION, AND APPLICATION THEREOF BEIJING INSTITUTE OF FASHION TECHNOLOGY (CN) 2025-06-12 US disclosed
CN-116217348-B Preparation method of 1, 2-di-n-propoxybenzene 万华化学集团股份有限公司 2024-05-03 CN disclosed
CN-117551039-A Aryl formamide compound, preparation method thereof and application of aryl formamide compound in resisting enterovirus EV71 武汉大学 2024-02-13 CN disclosed
WO-1993023357-A1 STILBENE DERIVATIVES AS ANTICANCER AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1993-11-25 WO disclosed
CN-1071930-A Inhibitor as the human immunodeficiency virus protease who treats acquired immune deficiency syndrome (AIDS) LILLY CO ELI (US) 1993-05-12 CN disclosed
CN-1057194-A Preparation and use of porphyrins FMC CORP (US) 1991-12-25 CN disclosed
EP-0323887-A2 Heat-sensitive diazo recording materials FUJI PHOTO FILM CO., LTD. (JP) 1989-07-12 EP disclosed
US-4355178-A BY ACYLATION OF THE CORRESPONDING UREA CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) 1982-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12415822-B2 Small molecule inhibitors selective for polo-like kinase protein PLK2, PLK4, PLK3 CYP3A4 4617/4885LMNA 1782/4885MEN1 4010/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.