Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 11/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732827 | 0.92 | PIK3CG (0.65) | PIK3CGPIK3CDMAPTMEN1KMT2A | |
| SCHEMBL2731738 | 0.86 | PIK3CG (0.60) | PIK3CGPIK3CDMAPTMEN1KMT2A | |
| SCHEMBL2730711 | 0.85 | PIK3CG (0.68) | PIK3CGPIK3CDMAPT | |
| SCHEMBL2729713 | 0.85 | PIK3CD (0.67) | PIK3CGPIK3CDMAPTACLY | |
| SCHEMBL2721975 | 0.84 | PIK3CG (0.63) | PIK3CGPIK3CDMAPTMEN1KMT2A | |
| SCHEMBL18174989 | 0.84 | MAPT (0.55) | PIK3CGPIK3CDMAPTMEN1KMT2A | |
| SCHEMBL4288631 | 0.83 | PIK3CG (0.59) | PIK3CGPIK3CDMAPTMEN1KMT2A | |
| SCHEMBL4288905 | 0.82 | PIK3CG (0.64) | PIK3CGPIK3CDMAPTMEN1KMT2A | |
| SCHEMBL2722453 | 0.82 | PIK3CG (0.63) | PIK3CGPIK3CDMAPTPOLB | |
| SCHEMBL15180097 | 0.81 | PIK3CG (0.62) | PIK3CGPIK3CDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052420-A1 | METHOD FOR PREPARING SUBSTITUTED N-(3-AMINO-QUINOXALIN-2-YL)-SULFONAMIDES AND THEIR INTERMEDIATES N-(3-CHLORO-QUINOXALIN-2-YL)SULFONAMIDES | MERCK SERONO S.A. GENEVA (CH) | 2012-04-26 | — | — | WO | disclosed |