Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4288292 | 0.91 | PIK3CG (0.59) | MAPTPOLBPIK3CGPIK3CD | |
| SCHEMBL2722971 | 0.85 | PIK3CG (0.57) | MAPTPIK3CGPIK3CD | |
| SCHEMBL10044545 | 0.84 | PIK3CG (0.58) | MAPTPOLBPIK3CGPIK3CDKMT2A | |
| SCHEMBL18175013 | 0.83 | PIK3CG (0.56) | MAPTPIK3CGPIK3CDKMT2AMEN1 | |
| SCHEMBL15193636 | 0.83 | PIK3CG (0.58) | MAPTPIK3CGPIK3CDKMT2AMEN1 | |
| SCHEMBL4288631 | 0.83 | PIK3CG (0.59) | MAPTPOLBPIK3CGPIK3CDKMT2A | |
| SCHEMBL2723304 | 0.83 | PIK3CD (0.68) | MAPTPIK3CGPIK3CD | |
| SCHEMBL2721570 | 0.83 | PIK3CG (0.60) | MAPTPIK3CGPIK3CDKMT2AMEN1 | |
| SCHEMBL2730711 | 0.82 | PIK3CG (0.68) | MAPTPIK3CGPIK3CD | |
| SCHEMBL2722966 | 0.81 | PIK3CG (0.68) | MAPTPIK3CGPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630129-B1 | QUINOXALINE DERIVATES | MERCK PATENT GMBH (DE) | 2016-10-26 | — | — | EP | disclosed |