Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14836593 | 0.81 | TSHR (0.44) | TSHRGABRR1GABRR2BLMTDP1 | |
| SCHEMBL1224792 | 0.81 | TSHR (0.44) | TSHRGABRR1GABRR2BLMTDP1 | |
| SCHEMBL14836590 | 0.81 | TSHR (0.44) | TSHRGABRR1GABRR2BLMTDP1 | |
| SCHEMBL1224793 | 0.81 | TSHR (0.44) | TSHRGABRR1GABRR2BLMTDP1 | |
| SCHEMBL6504438 | 0.76 | — | — | |
| SCHEMBL265515 | 0.76 | — | — | |
| SCHEMBL5746564 | 0.76 | — | — | |
| SCHEMBL6494908 | 0.76 | — | — | |
| SCHEMBL6504441 | 0.76 | — | — | |
| SCHEMBL11465249 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778645-B2 | Method for the production of glutaconate | BASF SE (DE) | 2014-07-15 | — | — | US | disclosed |
| US-20120021472-A1 | Method for the Production of Glutaconate | BASF SE (DE) | 2012-01-26 | — | — | US | disclosed |