⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453106 | 1.00 | — | — | |
| SCHEMBL11465249 | 1.00 | — | — | |
| SCHEMBL28825791 | 0.86 | GABRR1 (0.39) | — | |
| SCHEMBL17866776 | 0.82 | PPARA (0.43) | — | |
| SCHEMBL17866774 | 0.82 | PPARA (0.43) | — | |
| SCHEMBL15353 | 0.82 | — | — | |
| SCHEMBL15352 | 0.82 | — | — | |
| SCHEMBL12973059 | 0.82 | — | — | |
| SCHEMBL14497821 | 0.81 | TSHR (0.41) | — | |
| SCHEMBL9576396 | 0.81 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| CN-112390794-A | Preparation method of minodronic acid key intermediate | 鲁南制药集团股份有限公司 | 2021-02-23 | — | — | CN | disclosed |
| CN-112390823-A | Synthesis method of minodronic acid | 鲁南制药集团股份有限公司 | 2021-02-23 | — | — | CN | disclosed |
| US-8629126-B2 | Quinolone derivative or pharmaceutically acceptable salt thereof | ASTELLAS PHARMA INC. (JP) | 2014-01-14 | — | — | US | disclosed |
| US-8629126-B2 | Quinolone derivative or pharmaceutically acceptable salt thereof | ASTELLAS PHARMA INC. (JP) | 2014-01-14 | — | — | US | disclosed |
| US-20120136025-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2012-05-31 | — | — | US | disclosed |
| US-20120136025-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2012-05-31 | — | — | US | disclosed |
| US-8133882-B2 | Quinolone derivative or pharmaceutically acceptable salt thereof | ASTELLAS PHARMA INC (JP) | 2012-03-13 | — | — | US | disclosed |
| US-8133882-B2 | Quinolone derivative or pharmaceutically acceptable salt thereof | ASTELLAS PHARMA INC (JP) | 2012-03-13 | — | — | US | disclosed |
| EP-1995240-B1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2012-02-22 | — | — | EP | disclosed |
| US-20090197834-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-08-06 | — | — | US | disclosed |
| US-20090197834-A1 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-08-06 | — | — | US | disclosed |
| US-4239690-A | Antibiotics produced by Cytospora sp. W.F.P.L. 13A | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1980-12-16 | — | — | US | disclosed |
| US-4220718-A | GRAHAMIMYCINS | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1980-09-02 | — | — | US | disclosed |