Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL931094 | 0.85 | MAOB (0.45) | OXTRSLC22A12SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL15200325 | 0.83 | PIM1 (0.54) | SMN1; SMN2NPC1ALDH1A1RAB9ALMNA | |
| SCHEMBL21230516 | 0.82 | HPGD (0.47) | SLC22A12SMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL15180077 | 0.82 | CA1 (0.41) | OXTRSLC22A12SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL15200323 | 0.78 | HPGD (0.51) | SLC22A12NPC1ALDH1A1RAB9ALMNA | |
| SCHEMBL15200324 | 0.70 | SLC22A12 (0.43) | SLC22A12NPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL21230547 | 0.69 | MAPT (0.56) | SMN1; SMN2NPC1ALDH1A1RAB9ALMNA | |
| SCHEMBL22960809 | 0.68 | LMNA (0.63) | SMN1; SMN2NPC1ALDH1A1RAB9ALMNA | |
| SCHEMBL15349800 | 0.68 | LMNA (0.55) | SLC22A12SMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL4130113 | 0.68 | LMNA (0.51) | SLC22A12SMN1; SMN2NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052420-A1 | METHOD FOR PREPARING SUBSTITUTED N-(3-AMINO-QUINOXALIN-2-YL)-SULFONAMIDES AND THEIR INTERMEDIATES N-(3-CHLORO-QUINOXALIN-2-YL)SULFONAMIDES | MERCK SERONO S.A. GENEVA (CH) | 2012-04-26 | — | — | WO | disclosed |