SCHEMBL10045288

SCHEMBL10045288

O=S(=O)(O)NC1COC(COS(=O)(=O)O)CC1OS(=O)(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11934544 1.00
SCHEMBL732693 1.00
SCHEMBL14021805 0.86
SCHEMBL14723791 0.85
SCHEMBL11937055 0.85
SCHEMBL11913589 0.84
SCHEMBL11934549 0.83
SCHEMBL403204 0.83
SCHEMBL10045290 0.83
SCHEMBL10357880 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9877961-B2 Anticoagulant reversal agents PEROSPHERE INC. (US) 2018-01-30 US disclosed
US-20170056396-A1 ANTICOAGULANT REVERSAL AGENTS PINWHEEL THERAPEUTICS INC. 2017-03-02 US disclosed
US-20160361501-A1 MULTIPLE DOSE PHARMACEUTICAL COMPOSITIONS CONTAINING HEPARIN AND/OR HEPARIN-LIKE COMPOUNDS AND DEVICES AND METHODS FOR DELIVERING THE SAME VIRCHOW BIOTECH PVT. LTD. (IN) 2016-12-15 US disclosed
US-20140336369-A1 PROCESS FOR PREPARING HEPARINOIDS AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF APICORE US LLC (US) 2014-11-13 US disclosed
US-20130005954-A1 PROCESS FOR PREPARING HEPARINOIDS AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF APICORE, LLC 2013-01-03 US disclosed
US-8209131-B2 Inflammation, allergic diseases, metastatic cancers, pathogen infections; glycosaminoglycan related molecules CURTIN UNIVERSITY OF TECHNOLOGY (AU) 2012-06-26 US disclosed