SCHEMBL732693

SCHEMBL732693

O=S(=O)(O)NC1COC(COS(=O)(=O)O)C[C@H]1OS(=O)(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10045288 1.00
SCHEMBL11934544 1.00
SCHEMBL14021805 0.86
SCHEMBL14723791 0.85
SCHEMBL11937055 0.85
SCHEMBL11913589 0.84
SCHEMBL11934549 0.83
SCHEMBL403204 0.83
SCHEMBL10045290 0.83
SCHEMBL10357880 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10023603-B2 Preparation of monosaccharides, disaccharides, trisaccharides, and pentasaccharides of heparinoids FORMOSA LABORATORIES, INC. (TW) 2018-07-17 US disclosed
US-20170015695-A1 PREPARATION OF MONOSACCHARIDES, DISACCHARIDES, TRISACCHARIDES, AND PENTASACCHARIDES OF HEPARINOIDS FORMOSA LABORATORIES, INC. (TW) 2017-01-19 US disclosed
US-20160310521-A1 POLYSACCHARIDES COMPRISING TWO ANTITHROMBIN III-BINDING SITES, PREPARATION THEREOF AND USE THEREOF AS ANTITHROMBOTIC MEDICAMENTS SANOFI (FR) 2016-10-27 US disclosed
US-9243018-B2 Synthetic heparin pentasaccharides DR. REDDY'S LABORATORIES, SA (CH) 2016-01-26 US disclosed
US-9089484-B2 Pharmaceutical compositions of selective factor Xa inhibitors for oral administration MERRION RESEARCH III LIMITED (IE) 2015-07-28 US disclosed
US-20150005485-A1 SYNTHETIC HEPARIN PENTASACCHARIDES ALCHEMIA LIMITED (AU) 2015-01-01 US disclosed
US-20140336369-A1 PROCESS FOR PREPARING HEPARINOIDS AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF APICORE US LLC (US) 2014-11-13 US disclosed
US-8574544-B1 Pharmaceutical composition of nanoparticles GP MEDICAL, INC. (US) 2013-11-05 US disclosed
US-8535640-B1 Pharmaceutical composition of nanoparticles GP MEDICAL, INC. (US) 2013-09-17 US disclosed
US-8501711-B2 Acylated 1,6-anhydro decasaccharide and its use as an antithrombotic agent SANOFI (FR) 2013-08-06 US disclosed
US-20090142405-A1 Nanoparticles for protein drug delivery NANOMEGA MEDICAL CORPORATION 2009-06-04 US disclosed
US-7541445-B2 Synthetic heparin pentasaccharides ALCHEMIA LIMITED (AU) 2009-06-02 US disclosed
US-7541046-B1 Nanoparticles for protein drug delivery GP MEDICAL, INC. (US) 2009-06-02 US disclosed
US-20090011008-A1 Nanoparticles for protein drug delivery NANOMEGA MEDICAL CORPORATION 2009-01-08 US disclosed
US-20090004266-A1 Nanoparticles for protein drug delivery NANOMEGA MEDICAL CORPORATION 2009-01-01 US disclosed
US-7455830-B2 Nanoparticles for protein drug delivery GP MEDICAL, INC. (US) 2008-11-25 US disclosed
US-20080233200-A1 Nanoparticles for protein drug delivery NANOMEGA MEDICAL CORPORATION 2008-09-25 US disclosed
US-20080160078-A1 Nanoparticles for drug delivery GP MEDICAL, INC. 2008-07-03 US disclosed
US-7381716-B2 Nanoparticles for protein drug delivery GP MEDICAL, INC. (US) 2008-06-03 US disclosed
US-20070116771-A1 Nanoparticles for protein drug delivery NANOMEGA MEDICAL CORPORATION 2007-05-24 US disclosed