Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3920677 | 0.92 | TDP1 (0.53) | TDP1L3MBTL1CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL26645944 | 0.80 | CHRNB2 (0.49) | TDP1L3MBTL1CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL31686137 | 0.80 | CHRNB2 (0.49) | TDP1L3MBTL1CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL28705794 | 0.80 | TDP1 (0.57) | TDP1L3MBTL1CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL29438513 | 0.80 | TDP1 (0.57) | TDP1L3MBTL1CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL12282537 | 0.78 | CHRNA7 (0.50) | TDP1L3MBTL1CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL9668987 | 0.77 | TDP1 (0.51) | TDP1L3MBTL1CHRNA7CYP2A6HRH1 | |
| SCHEMBL7474917 | 0.74 | CHRNA7 (0.58) | TDP1L3MBTL1CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL22229849 | 0.74 | CHRNA7 (0.58) | TDP1L3MBTL1CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL104468 | 0.73 | CHRNA7 (0.57) | TDP1L3MBTL1CHRNB2CHRNA4CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114813-B2 | Heat transferrable dye in resin containing polyvinyl acetal modified with ketone | FUJIFILM CORPORATION (JP) | 2012-02-14 | — | — | US | disclosed |