Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308991 | 0.96 | MAOB (0.72) | MAOBMEN1KMT2AALOX5LMNA | |
| SCHEMBL7743406 | 0.91 | MAOB (0.67) | MAOBMEN1KMT2AALOX5 | |
| SCHEMBL4674930 | 0.89 | MEN1 (0.70) | MAOBMEN1KMT2AALOX5LMNA | |
| SCHEMBL31418062 | 0.89 | MAOB (0.64) | MAOBMEN1KMT2AALOX5LMNA | |
| SCHEMBL347904 | 0.87 | MAOB (0.62) | MAOBMEN1KMT2AALOX5LMNA | |
| SCHEMBL2150956 | 0.87 | MAOB (0.62) | MAOBMEN1KMT2AALOX5LMNA | |
| SCHEMBL4073348 | 0.87 | MAOB (0.62) | MAOBMEN1KMT2AALOX5LMNA | |
| SCHEMBL2226602 | 0.87 | MAOB (0.62) | MAOBMEN1KMT2AALOX5LMNA | |
| SCHEMBL221836 | 0.87 | MAOB (0.62) | MAOBMEN1KMT2AALOX5LMNA | |
| SCHEMBL22489859 | 0.87 | MAOB (0.63) | MAOBMEN1KMT2AALOX5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240216357-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
| US-20240216357-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
| US-20230067037-A1 | CONJUGATED CHEMICAL INDUCERS OF DEGRADATION AND METHODS OF USE | GENENTECH, INC. (US) | 2023-03-02 | — | — | US | disclosed |
| WO-2019040792-A1 | SECOND GENERATION GRP94-SELECTIVE INHIBITORS | UNIVERSITY OF KANSAS (US) | 2019-02-28 | — | — | WO | disclosed |
| EP-2744778-B1 | META-SUBSTITUTED BIPHENYL PERIPHERALLY RESTRICTED FAAH INHIBITORS | UNIV CALIFORNIA (US) | 2019-01-16 | — | — | EP | disclosed |
| EP-2818531-B1 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |
| EP-2818531-B1 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |
| US-9567526-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-02-14 | — | — | US | disclosed |
| EP-2605767-B1 | SHIP1 MODULATORS AND RELATED METHODS | UNIV BRITISH COLUMBIA (CA) | 2016-07-27 | — | — | EP | disclosed |
| EP-2605767-B1 | SHIP1 MODULATORS AND RELATED METHODS | UNIV BRITISH COLUMBIA (CA) | 2016-07-27 | — | — | EP | disclosed |
| US-9000050-B2 | SHIP1 modulators and related methods | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2015-04-07 | — | — | US | disclosed |
| US-9000050-B2 | SHIP1 modulators and related methods | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2015-04-07 | — | — | US | disclosed |
| EP-2818531-A1 | Polymerisable compounds and the use thereof in liquid-crystal displays | Merck Patent GmbH (DE) | 2014-12-31 | — | — | EP | disclosed |
| US-20140375943-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2014-12-25 | — | — | US | disclosed |
| EP-2744778-A2 | META-SUBSTITUTED BIPHENYL PERIPHERALLY RESTRICTED FAAH INHIBITORS | The Regents of the University of California (US) | 2014-06-25 | — | — | EP | disclosed |
| US-20130217674-A1 | SHIP1 MODULATORS AND RELATED METHODS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-08-22 | — | — | US | disclosed |
| US-20130217674-A1 | SHIP1 MODULATORS AND RELATED METHODS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-08-22 | — | — | US | disclosed |
| US-20130217674-A1 | SHIP1 MODULATORS AND RELATED METHODS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-08-22 | — | — | US | disclosed |
| WO-2013028570-A2 | META-SUBSTITUTED BIPHENYL PERIPHERALLY RESTRICTED FAAH INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-02-28 | — | — | WO | disclosed |
| WO-2012024682-A1 | SHIP1 MODULATORS AND RELATED METHODS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230067037-A1 | CONJUGATED CHEMICAL INDUCERS OF DEGRADATION AND METHODS OF USE | ADRM1, SSB, FCER2 | MAOB 3032/4885MEN1 4419/4885KMT2A 4147/4885 |
| US-20240216357-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | KDM1A, TET1, KDM3A | MAOB 431/4885MEN1 1113/4885KMT2A 43/4885 |
| US-20130217674-A1 | SHIP1 MODULATORS AND RELATED METHODS | PPM1D, PPP1R1B, PPM1G | MAOB 4360/4885MEN1 1626/4885KMT2A 3805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.