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Sugi Predict / Targets / ADRM1

ADRM1

Proteasomal ubiquitin receptor ADRM1 · Q16186 · ADRM1 on Sugi Atlas →

6,069 patent compounds predicted against ADRM1, 4,640 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL1478606 SCHEMBL1478606 0.58 12/20
SCHEMBL607010 SCHEMBL607010 0.56 12/20
SCHEMBL608381 SCHEMBL608381 0.53 12/20
SCHEMBL3170187 SCHEMBL3170187 0.51 12/20
SCHEMBL606616 SCHEMBL606616 0.51 12/20
SCHEMBL1477637 SCHEMBL1477637 0.57 11/20
SCHEMBL607972 SCHEMBL607972 0.55 11/20
SCHEMBL608782 SCHEMBL608782 0.54 11/20
SCHEMBL609278 SCHEMBL609278 0.54 11/20
SCHEMBL607553 SCHEMBL607553 0.54 11/20
SCHEMBL605822 SCHEMBL605822 0.54 11/20
SCHEMBL606932 SCHEMBL606932 0.53 11/20
SCHEMBL1477893 SCHEMBL1477893 0.53 11/20
SCHEMBL608362 SCHEMBL608362 0.53 11/20
SCHEMBL608599 SCHEMBL608599 0.53 11/20
SCHEMBL1327441 SCHEMBL1327441 0.53 11/20
SCHEMBL605129 SCHEMBL605129 0.52 11/20
SCHEMBL3170843 SCHEMBL3170843 0.52 11/20
SCHEMBL608009 SCHEMBL608009 0.52 11/20
SCHEMBL1478157 SCHEMBL1478157 0.52 11/20

Clinical trials — most relevant to ADRM1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Does Aldosterone Cause Hypertension by a Non-Renal Mechanism? PHASE4UNKNOWN
Seviteronel in Combination With Chemotherapy in Androgen-receptor Positive Metastatic Triple-negative Breast Cancer PHASE1/PHASE2RECRUITING
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers PHASE2NOT_YET_RECRUITING
Colchicine for Amyotrophic Lateral Sclerosis PHASE2COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
Nilotinib in Huntington's Disease PHASE1UNKNOWN
Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease EARLY_PHASE1RECRUITING
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure nanCOMPLETED
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors nanNOT_YET_RECRUITING
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men nanRECRUITING
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma nanCOMPLETED
The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
National Active Surveillance Network and Pharmacogenomics of Adverse Drug Reactions in Children nanRECRUITING
Exercise Therapy to Reduce Heart Failure Symptoms; Sorting Mechanisms of Benefit nanCOMPLETED
Low Dose Melphalan and Bortezomib for AML and High-Risk MDS nanCOMPLETED
Dysfunctions of Human Muscle Stem Cells in Sepsis nanCOMPLETED
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease nanUNKNOWN
Safety and Tolerability of a Nutritional Formula Designed to Aid in Maintenance of Muscle During Periods of Caloric Restriction in Adults nanNOT_YET_RECRUITING
Time Course for Fasting-induced Autophagy in Humans nanWITHDRAWN
Genetic Analysis to Predict the Development of Paget's Disease nanACTIVE_NOT_RECRUITING
Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract nanUNKNOWN
Biological Markers in Parkinson's Disease nanCOMPLETED
The Genetic Characterization of Dementia nanCOMPLETED
The Locus Coeruleus, Norepinephrine and Cognitive Aging nanACTIVE_NOT_RECRUITING
TAKO-TSUBO Cardiomyopathy and Genetic nanCOMPLETED
Care to Plan: a Tailored Resource for Family Members of Persons With Dementia nanCOMPLETED
Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population nanCOMPLETED
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a ADRM1 binder may also engage these)

ProteinNameSimilarity
Q98SH3 — 1.000 Q98SH3 →
Q9JMB5 — 1.000 Q9JMB5 →
A1L5A6 — 1.000 A1L5A6 →
Q9JKV1 — 0.999 Q9JKV1 →
Q6NZ09 — 0.998 Q6NZ09 →
Q6GN67 — 0.998 Q6GN67 →
Q7ZXD6 — 0.997 Q7ZXD6 →
Q6P877 — 0.997 Q6P877 →
Q84L31 — 0.970 Q84L31 →
Q95107 — 0.959 Q95107 →
O60784 — 0.958 O60784 →
Q84L30 — 0.958 Q84L30 →
O48726 — 0.957 O48726 →
O08816 — 0.957 O08816 →
O35226 — 0.957 O35226 →
A2VDN6 — 0.957 A2VDN6 →
O88746 — 0.956 O88746 →
O12940 — 0.956 O12940 →
Q84L32 — 0.956 Q84L32 →
Q68FJ8 — 0.956 Q68FJ8 →
Q84L33 — 0.955 Q84L33 →
SF3A1 Splicing factor 3A subunit 1 0.955 landscape →
UBQLN1 Ubiquilin-1 0.955 landscape →
P70483 — 0.955 P70483 →
Q4WTC0 — 0.955 Q4WTC0 →
Q5R684 — 0.954 Q5R684 →
Q90828 — 0.954 Q90828 →
Q9SII9 — 0.953 Q9SII9 →
Q5ZJ85 — 0.953 Q5ZJ85 →
Q8K4Z5 — 0.953 Q8K4Z5 →