SCHEMBL10046176

SCHEMBL10046176

COc1cc(C/C=I/CC/C=C(\C)CC[C@H]2OC2(C)C)cc(OC)c1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LSS P48449 9/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL673340 0.85 LSS (0.52) LSS
SCHEMBL10046197 0.85 LSS (0.52) LSS
SCHEMBL673339 0.85 LSS (0.52) LSS
SCHEMBL673338 0.85 LSS (0.52) LSS
SCHEMBL15194626 0.85 LSS (0.52) LSS
SCHEMBL672094 0.79 LSS (0.48) LSS
SCHEMBL672093 0.79 LSS (0.48) LSS
SCHEMBL10046174 0.76
SCHEMBL14493979 0.72 LSS (0.48) LSS
SCHEMBL17938148 0.66 PPARG (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012024682-A1 SHIP1 MODULATORS AND RELATED METHODS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2012-02-23 WO disclosed