Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046197 | 1.00 | LSS (0.52) | LSSDHODH | |
| SCHEMBL15194626 | 1.00 | LSS (0.52) | LSSDHODH | |
| SCHEMBL673340 | 1.00 | LSS (0.52) | LSSDHODH | |
| SCHEMBL673339 | 1.00 | LSS (0.52) | LSSDHODH | |
| SCHEMBL672094 | 0.93 | LSS (0.48) | LSSDHODH | |
| SCHEMBL672093 | 0.93 | LSS (0.48) | LSSDHODH | |
| SCHEMBL10046176 | 0.85 | LSS (0.41) | LSS | |
| SCHEMBL10046173 | 0.81 | PPARG (0.52) | — | |
| SCHEMBL17938148 | 0.81 | PPARG (0.52) | — | |
| SCHEMBL14493979 | 0.77 | LSS (0.48) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2605767-B1 | SHIP1 MODULATORS AND RELATED METHODS | UNIV BRITISH COLUMBIA (CA) | 2016-07-27 | — | — | EP | disclosed |
| EP-2605767-B1 | SHIP1 MODULATORS AND RELATED METHODS | UNIV BRITISH COLUMBIA (CA) | 2016-07-27 | — | — | EP | disclosed |
| US-9000050-B2 | SHIP1 modulators and related methods | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2015-04-07 | — | — | US | disclosed |
| US-9000050-B2 | SHIP1 modulators and related methods | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2015-04-07 | — | — | US | disclosed |
| US-9000050-B2 | SHIP1 modulators and related methods | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2015-04-07 | — | — | US | disclosed |
| US-20130217674-A1 | SHIP1 MODULATORS AND RELATED METHODS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-08-22 | — | — | US | disclosed |
| US-20130217674-A1 | SHIP1 MODULATORS AND RELATED METHODS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-08-22 | — | — | US | disclosed |
| US-20130217674-A1 | SHIP1 MODULATORS AND RELATED METHODS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-08-22 | — | — | US | disclosed |
| EP-2605767-A1 | SHIP1 MODULATORS AND RELATED METHODS | The University Of British Columbia (CA) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012024682-A1 | SHIP1 MODULATORS AND RELATED METHODS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217674-A1 | SHIP1 MODULATORS AND RELATED METHODS | PPM1D, PPP1R1B, PPM1G | LSS 3768/4885DHODH 4425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.