⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14474695 | 1.00 | — | — | |
| SCHEMBL31620917 | 0.85 | — | — | |
| SCHEMBL21129616 | 0.83 | MMP2 (0.30) | — | |
| SCHEMBL17324364 | 0.83 | — | — | |
| SCHEMBL13464156 | 0.82 | — | — | |
| SCHEMBL21664953 | 0.82 | — | — | |
| SCHEMBL23802491 | 0.81 | — | — | |
| SCHEMBL28430322 | 0.81 | — | — | |
| SCHEMBL28455486 | 0.81 | — | — | |
| SCHEMBL13445911 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137619-A1 | ANTI-CLAUDIN, BIS-BENZIMID AZOLE STING AGONIST IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024129956-A1 | THIENOAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| US-11826485-B2 | Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices | HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11739166-B2 | Reactive polysaccharide-based hemostatic agent | DAVOL INC. (US) | 2023-08-29 | — | — | US | disclosed |
| WO-2022204536-A1 | 2-AMINO-4-CARBOXAMIDE-BENZAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |
| WO-2022125884-A1 | IMMUNOCONJUGATES COMPRISING AN ANTI-CEA ANTIBODY LINKED BY CONJUGATION TO ONE OR|MORE 8-HET-2- AMINOBENZAZEPINE DERIVATIVES USEFUL IN TREATING CANCER | BOLT BIOTHERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |
| WO-2022125908-A1 | ANTI-PD-L1 IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |
| WO-2022125891-A2 | ANTI-CEA IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |
| WO-2022125915-A1 | ANTI-HER2 IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |
| WO-2022125904-A1 | ANTI-HER2 IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |
| US-20120082728-A1 | MULTIFUNCTIONAL STEALTH NANOPARTICULES FOR BIOMEDICAL USE | UNIVERSITE DE STRASBOURG (FR) | 2012-04-05 | — | — | US | disclosed |
| US-20110111388-A1 | METHOD FOR THE SENSITIVE DETECTION OF POLYAMINO ACIDS AND OTHER MACRO-MOLECULES | XYNTEC CHEMIE GMBH WOLFEN (DE) | 2011-05-12 | — | — | US | disclosed |
| US-20110111388-A1 | METHOD FOR THE SENSITIVE DETECTION OF POLYAMINO ACIDS AND OTHER MACRO-MOLECULES | XYNTEC CHEMIE GMBH WOLFEN (DE) | 2011-05-12 | — | — | US | disclosed |
| US-20100069927-A1 | Polymeric Masking Materials for Spanning Wound Sites, and Methods of Use Thereof | HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) | 2010-03-18 | — | — | US | disclosed |
| US-20090312530-A1 | Processes for the convergent synthesis of calicheamicin derivatives | WYETH (US) | 2009-12-17 | — | — | US | disclosed |
| US-20070196454-A1 | Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices | HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) | 2007-08-23 | — | — | US | disclosed |
| US-20070197455-A1 | Processes for the convergent synthesis of calicheamicin derivatives | WYETH (US) | 2007-08-23 | — | — | US | disclosed |
| EP-1198254-B1 | CARRIER-DRUG CONJUGATE | KTB TUMORFORSCHUNGS GMBH (DE) | 2007-08-15 | — | — | EP | disclosed |
| US-7176256-B2 | Reacting by crosslinking a first synthetic polymer containing multiple nucleophilic groups such as amino groups, with a second synthetic polymer containing multiple electrophilic groups such as succinimidyl groups to covalently bind them; use to prevent surgical adhesions, coat implants | ANGIOTECH PHARMACEUTICALS (US), INC. (US) | 2007-02-13 | — | — | US | disclosed |
| WO-2007001926-A2 | LOW-SWELLING HYDROGEL SEALANTS FOR WOUND REPAIR | HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) | 2007-01-04 | — | — | WO | disclosed |