Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.30 |
| ▸ | GABRD | O14764 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.30 |
| ▸ | GABRE | P78334 | 2/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.30 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046223 | 1.00 | DPP4 (0.32) | DPP4DPP8DPP9GFPT1CYP2D6 | |
| SCHEMBL10046222 | 1.00 | DPP4 (0.32) | DPP4DPP8DPP9GFPT1CYP2D6 | |
| SCHEMBL19891849 | 0.83 | DPP4 (0.33) | DPP4DPP8DPP9 | |
| SCHEMBL18821637 | 0.83 | — | — | |
| SCHEMBL10046241 | 0.82 | CYP2D6 (0.32) | CYP2D6CYP2C19 | |
| SCHEMBL10046240 | 0.82 | CYP2D6 (0.32) | CYP2D6CYP2C19 | |
| SCHEMBL10046239 | 0.82 | CYP2D6 (0.32) | CYP2D6CYP2C19 | |
| SCHEMBL25132012 | 0.81 | ANPEP (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12132309 | 0.81 | ANPEP (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13363467 | 0.81 | ANPEP (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127518-A1 | CHITOSAN-DERIVATIVE COMPOUNDS AND METHODS OF CONTROLLING MICROBIAL POPULATIONS | UNITED STATES GOVERNMENT | 2018-05-10 | — | — | US | disclosed |
| US-20180127518-A1 | CHITOSAN-DERIVATIVE COMPOUNDS AND METHODS OF CONTROLLING MICROBIAL POPULATIONS | UNITED STATES GOVERNMENT | 2018-05-10 | — | — | US | disclosed |
| EP-3311823-A1 | METHODS AND COMPOSITIONS FOR DISRUPTING BIOFILM UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS | Synedgen, Inc. (US) | 2018-04-25 | — | — | EP | disclosed |
| US-9732164-B2 | Chitosan-derivative compounds and methods of controlling microbial populations | SYNEDGEN, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-9732164-B2 | Chitosan-derivative compounds and methods of controlling microbial populations | SYNEDGEN, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| EP-2473042-B1 | METHODS AND COMPOSITIONS FOR DISRUPTING BIOFILM UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS | SYNEDGEN INC (US) | 2017-08-02 | — | — | EP | disclosed |
| US-20160060362-A1 | CHITOSAN-DERIVATIVE COMPOUNDS AND METHODS OF CONTROLLING MICROBIAL POPULATIONS | UNITED STATES GOVERNMENT | 2016-03-03 | — | — | US | disclosed |
| US-20160060362-A1 | CHITOSAN-DERIVATIVE COMPOUNDS AND METHODS OF CONTROLLING MICROBIAL POPULATIONS | UNITED STATES GOVERNMENT | 2016-03-03 | — | — | US | disclosed |
| US-9029351-B2 | Chitosan-derivative compounds and methods of controlling microbial populations | SYNEDGEN, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-20140301955-A1 | CHITOSAN-DERIVATIVE COMPOUNDS AND METHODS OF CONTROLLING MICROBIAL POPULATIONS | SYNEDGEN, INC. (US) | 2014-10-09 | — | — | US | disclosed |
| US-8658775-B2 | Chitosan-derivative compounds and methods of controlling microbial populations | UNITED STATES GOVERNMENT | 2014-02-25 | — | — | US | disclosed |
| US-8658775-B2 | Chitosan-derivative compounds and methods of controlling microbial populations | UNITED STATES GOVERNMENT | 2014-02-25 | — | — | US | disclosed |
| US-20120329753-A1 | CHITOSAN-DERIVATIVE COMPOUNDS AND METHODS OF CONTROLLING MICROBIAL POPULATIONS | UNITED STATES GOVERNMENT | 2012-12-27 | — | — | US | disclosed |
| US-20120329753-A1 | CHITOSAN-DERIVATIVE COMPOUNDS AND METHODS OF CONTROLLING MICROBIAL POPULATIONS | UNITED STATES GOVERNMENT | 2012-12-27 | — | — | US | disclosed |
| US-8119780-B2 | Chitosan-derivative compounds and methods of controlling microbial populations | SYNEDGEN, INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20070281904-A1 | Chitosan-derivative compounds and methods of controlling microbial populations | UNITED STATES GOVERNMENT | 2007-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127518-A1 | CHITOSAN-DERIVATIVE COMPOUNDS AND METHODS OF CONTROLLING MICROBIAL POPULATIONS | ARG1, NRDC, CHIA | DPP4 111/4885DPP8 538/4885DPP9 201/4885 |
| US-20120329753-A1 | CHITOSAN-DERIVATIVE COMPOUNDS AND METHODS OF CONTROLLING MICROBIAL POPULATIONS | ARG1, NRDC, CHIA | DPP4 111/4885DPP8 538/4885DPP9 201/4885 |
| US-20070281904-A1 | Chitosan-derivative compounds and methods of controlling microbial populations | ARG1, NRDC, CHIA | DPP4 111/4885DPP8 538/4885DPP9 201/4885 |
| US-20140301955-A1 | CHITOSAN-DERIVATIVE COMPOUNDS AND METHODS OF CONTROLLING MICROBIAL POPULATIONS | ARG1, NRDC, CHIA | DPP4 111/4885DPP8 538/4885DPP9 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.