SCHEMBL10046227

SCHEMBL10046227

CC(C)C(=O)[C@H](N)CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10460020 1.00
SCHEMBL10046224 1.00
SCHEMBL4761845 0.79 GABRR1 (0.46)
SCHEMBL21122518 0.79 GABRR1 (0.46)
SCHEMBL12278736 0.79 GABRR1 (0.46)
SCHEMBL2625545 0.78
SCHEMBL4761841 0.78
SCHEMBL21345128 0.78
SCHEMBL12863852 0.78
SCHEMBL7555148 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11911412-B2 Derivatized chitosan polymers and methods of treating vascular disorders SYNEDGEN, INC. (US) 2024-02-27 US disclosed
US-11786547-B2 Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds SYNEDGEN, INC. (US) 2023-10-17 US disclosed
US-11786547-B2 Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds SYNEDGEN, INC. (US) 2023-10-17 US disclosed
US-11717532-B2 Methods and compositions for treating wounds utilizing chitosan compounds SYNEDGEN, INC. (US) 2023-08-08 US disclosed
US-11717532-B2 Methods and compositions for treating wounds utilizing chitosan compounds SYNEDGEN, INC. (US) 2023-08-08 US disclosed
US-20230201248-A1 COMPOSITIONS AND METHODS OF USE THEREOF SYNEDGEN, INC. 2023-06-29 US disclosed
US-20230201248-A1 COMPOSITIONS AND METHODS OF USE THEREOF SYNEDGEN, INC. 2023-06-29 US disclosed
US-20230021050-A1 COMPOSITIONS AND METHODS OF THEIR USE SYNEDGEN, INC. 2023-01-19 US disclosed
US-20220160754-A1 DERIVATIZED CHITOSAN POLYMERS AND METHODS OF TREATING VASCULAR DISORDERS SYNEDGEN, INC. 2022-05-26 US disclosed
US-20210386774-A1 METHODS FOR TREATMENT OR PREVENTION OF DAMAGE RESULTING FROM RADIATION, TRAUMA OR SHOCK SYNEDGEN, INC. 2021-12-16 US disclosed
US-20120301408-A1 ORAL CARE METHODS AND COMPOSITIONS UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS UNITED STATES GOVERNMENT 2012-11-29 US disclosed
US-20120295355-A1 NUCLEIC ACID DELIVERY USING MODIFIED CHITOSANS BAKER SHENDA (US) 2012-11-22 US disclosed
US-8119780-B2 Chitosan-derivative compounds and methods of controlling microbial populations SYNEDGEN, INC. (US) 2012-02-21 US disclosed
WO-2011127144-A1 METHODS AND COMPOSITIONS FOR TREATING WOUNDS UTILIZING CHITOSAN COMPOUNDS SYNEDGEN INC. (US) 2011-10-13 WO disclosed
WO-2011028968-A1 ORAL CARE METHODS AND COMPOSITIONS UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS SYNEDGEN, INC. (US) 2011-03-10 WO disclosed
US-20100137193-A1 CHITOSAN DERIVATIVES TO TREAT ANIMALS OR OPTIMIZE ANIMAL HEALTH SYNEDGEN INC. (US) 2010-06-03 US disclosed
US-20100130443-A1 CHITOSAN DERIVATIVES, COMPOSITIONS AND RELATED METHODS OF USE SYNEDGEN INC. (US) 2010-05-27 US disclosed
WO-2010056927-A1 CHITOSAN DERIVATIVES ALONE OR IN COMBINATION FOR THE TREATMENT OF MDR MICROBIAL INFECTIONS SYNEDGEN, INC. (US) 2010-05-20 WO disclosed
US-20100056474-A1 Methods and Compositions for the Prevention of and Treatment of Infections Utilizing Chitosan-Derivative Compounds UNITED STATES GOVERNMENT 2010-03-04 US disclosed
US-20070281904-A1 Chitosan-derivative compounds and methods of controlling microbial populations UNITED STATES GOVERNMENT 2007-12-06 US disclosed