SCHEMBL10046350

SCHEMBL10046350

C=C(/C=c1/ccccc1=C)c1c2c(cc3c4ccccc4c4cccc2c43)c(-c2ccc3ccccc3c2)c2c3cccc4c(-c5cc(-c6ccccc6)nc(-c6ccccc6)c5)ccc(c12)c43

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10015405 0.82 CYP1A1 (0.39) MEN1KMT2A
SCHEMBL25005766 0.71 MEN1 (0.36) MEN1KMT2A
SCHEMBL25006625 0.71 MEN1 (0.36) MEN1KMT2A
SCHEMBL14700535 0.70 CYP1A1 (0.38) —
SCHEMBL22652712 0.67 ERN1 (0.35) —
SCHEMBL10015419 0.66 MEN1 (0.35) MEN1KMT2A
SCHEMBL23349018 0.64 KDM1A (0.37) MEN1KMT2A
SCHEMBL23349048 0.64 KDM1A (0.37) MEN1KMT2A
SCHEMBL15859016 0.63 PIK3CD (0.35) MEN1KMT2A
SCHEMBL22916738 0.63 CYP11B1 (0.38) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940413-B2 Organic compound having acenaphtho[1,2-k]benzo[e]acephenanthrene derivative, light-emitting device, and image display apparatus CANON KABUSHIKI KAISHA (JP) 2015-01-27 — — US disclosed
US-20120025183-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-02-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120025183-A1 NOVEL ORGANIC COMPOUND, LIGHT-EMITTING DEVICE, AND IMAGE DISPLAY APPARATUS ACE, ACE2, AGTR1 MEN1 3665/4885KMT2A 2118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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