Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765129 | 0.92 | KAT2B (0.42) | KAT2BKMT2AMAPTMEN1HPGD | |
| SCHEMBL10046499 | 0.91 | KMT2A (0.37) | KAT2BKMT2AMAPTMEN1HPGD | |
| SCHEMBL10046421 | 0.90 | KAT2B (0.39) | KAT2BKMT2AMAPTMEN1HPGD | |
| SCHEMBL765562 | 0.90 | KAT2B (0.39) | KAT2BKMT2AMAPTMEN1HPGD | |
| SCHEMBL14605533 | 0.87 | ALDH1A1 (0.43) | KAT2BKMT2AMAPTMEN1TSHR | |
| SCHEMBL15423259 | 0.85 | KMT2A (0.37) | KAT2BKMT2AMAPTMEN1HPGD | |
| SCHEMBL14605534 | 0.81 | KMT2A (0.36) | KAT2BKMT2AMAPTMEN1HPGD | |
| SCHEMBL764385 | 0.80 | KMT2A (0.36) | KAT2BKMT2AMAPTALDH1A1 | |
| SCHEMBL765094 | 0.80 | KAT2B (0.46) | KAT2BKMT2AMAPTMEN1HPGD | |
| SCHEMBL765112 | 0.80 | CNR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325169-A9 | LISOFYLLINE ANALOGUES AND THEIR PHARMEACUETICAL USES | University Of Virginia Patent Foundation (US) | 2012-03-21 | — | — | EP | disclosed |
| EP-2325169-A2 | Lisofylline analogues and their pharmeacuetical uses | University Of Virginia Patent Foundation (US) | 2011-05-25 | — | — | EP | disclosed |