Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL764351 | 0.94 | CNR1 (0.35) | CNR2CNR1ACHEPPARG | |
| SCHEMBL12443687 | 0.87 | CNR2 (0.43) | CNR2CNR1ACHEMEN1MAPT | |
| SCHEMBL12443253 | 0.87 | CNR2 (0.43) | CNR2CNR1ACHEMEN1MAPT | |
| SCHEMBL765580 | 0.85 | CNR1 (0.31) | CNR2CNR1ACHE | |
| SCHEMBL764377 | 0.85 | CNR1 (0.31) | CNR2CNR1ACHE | |
| SCHEMBL765094 | 0.81 | KAT2B (0.46) | CNR2CNR1ACHEMEN1MAPT | |
| SCHEMBL765112 | 0.80 | CNR1 (0.33) | CNR2CNR1ACHE | |
| SCHEMBL3319604 | 0.75 | CNR2 (0.51) | CNR2CNR1ACHEMEN1MAPT | |
| SCHEMBL3312575 | 0.75 | CNR2 (0.51) | CNR2CNR1ACHEMEN1MAPT | |
| SCHEMBL14605533 | 0.74 | ALDH1A1 (0.43) | CNR2CNR1ACHEMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325169-A9 | LISOFYLLINE ANALOGUES AND THEIR PHARMEACUETICAL USES | University Of Virginia Patent Foundation (US) | 2012-03-21 | — | — | EP | disclosed |
| EP-2325169-A2 | Lisofylline analogues and their pharmeacuetical uses | University Of Virginia Patent Foundation (US) | 2011-05-25 | — | — | EP | disclosed |