Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14213258 | 0.97 | CA12 (0.33) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL10046753 | 0.97 | CA12 (0.33) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL14213253 | 0.90 | KDM4E (0.33) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL13992519 | 0.86 | CA1 (0.36) | CA12CA1CA2CA9 | |
| SCHEMBL10046761 | 0.84 | L3MBTL1 (0.38) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL10046759 | 0.81 | L3MBTL1 (0.38) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL14213259 | 0.79 | L3MBTL1 (0.37) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL10046756 | 0.79 | KDM4E (0.40) | CA12CA1CA2CA9 | |
| SCHEMBL14681006 | 0.78 | SCN9A (0.37) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL10046751 | 0.77 | HTR1D (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207228-B2 | Calixarene-based peptide conformation mimetics, methods of use, and methods of making | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-06-26 | — | — | US | disclosed |
| US-20080300164-A1 | Calixarene-Based Peptide Conformation Mimetics, Methods of Use, and Methods of Making | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300164-A1 | Calixarene-Based Peptide Conformation Mimetics, Methods of Use, and Methods of Making | CLSPN, BID, CALU | CA12 745/4885CA1 600/4885CA2 500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.