Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mitobronitol SCHEMBL23128365 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNAL3MBTL1TDP1 | |
| Mitobronitol SCHEMBL8500 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNAL3MBTL1TDP1 | |
| Mitobronitol SCHEMBL8456 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNAL3MBTL1TDP1 | |
| Mitobronitol SCHEMBL24408845 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNAL3MBTL1TDP1 | |
| Mitolactol SCHEMBL8455 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNAL3MBTL1TDP1 | |
| SCHEMBL3798965 | 0.87 | ALDH1A1 (0.75) | ALDH1A1LMNAL3MBTL1TDP1 | |
| SCHEMBL8648464 | 0.84 | ALDH1A1 (0.71) | ALDH1A1LMNAL3MBTL1TDP1 | |
| SCHEMBL561011 | 0.82 | — | — | |
| SCHEMBL10837948 | 0.82 | — | — | |
| SCHEMBL4421089 | 0.78 | ALDH1A1 (0.60) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9630938-B2 | Method of synthesis of substituted hexitols such as dianhydrogalactitol | DELMAR PHARMACEUTICALS, INC. (CA) | 2017-04-25 | — | — | US | disclosed |
| US-9630938-B2 | Method of synthesis of substituted hexitols such as dianhydrogalactitol | DELMAR PHARMACEUTICALS, INC. (CA) | 2017-04-25 | — | — | US | disclosed |
| US-20150329511-A1 | METHOD OF SYNTHESIS OF SUBSTITUTED HEXITOLS SUCH AS DIANHYDROGALACTITOL | DEL MAR PHARMACEUTICALS (BC) LTD. (CA) | 2015-11-19 | — | — | US | disclosed |
| US-20150329511-A1 | METHOD OF SYNTHESIS OF SUBSTITUTED HEXITOLS SUCH AS DIANHYDROGALACTITOL | DEL MAR PHARMACEUTICALS (BC) LTD. (CA) | 2015-11-19 | — | — | US | disclosed |
| US-9085544-B2 | Method of synthesis of substituted hexitols such as dianhydrogalactitol | DEL MAR PHARMACEUTICALS (CA) | 2015-07-21 | — | — | US | disclosed |
| US-9085544-B2 | Method of synthesis of substituted hexitols such as dianhydrogalactitol | DEL MAR PHARMACEUTICALS (CA) | 2015-07-21 | — | — | US | disclosed |
| US-8921585-B2 | Method of synthesis of substituted hexitols such as dianhydrogalactitol | DEL MAR PHARMACEUTICALS (CA) | 2014-12-30 | — | — | US | disclosed |
| US-8921585-B2 | Method of synthesis of substituted hexitols such as dianhydrogalactitol | DEL MAR PHARMACEUTICALS (CA) | 2014-12-30 | — | — | US | disclosed |
| US-20140155638-A1 | METHOD OF SYNTHESIS OF SUBSTITUTED HEXITOLS SUCH AS DIANHYDROGALACTITOL | DEL MAR PHARMACEUTICALS (BC) LTD. (CA) | 2014-06-05 | — | — | US | disclosed |
| US-20140155638-A1 | METHOD OF SYNTHESIS OF SUBSTITUTED HEXITOLS SUCH AS DIANHYDROGALACTITOL | DEL MAR PHARMACEUTICALS (BC) LTD. (CA) | 2014-06-05 | — | — | US | disclosed |
| US-20140066642-A1 | METHOD OF SYNTHESIS OF SUBSTITUTED HEXITOLS SUCH AS DIANHYDROGALACTITOL | DEL MAR PHARMACEUTICALS (CA) | 2014-03-06 | — | — | US | disclosed |
| US-20140066642-A1 | METHOD OF SYNTHESIS OF SUBSTITUTED HEXITOLS SUCH AS DIANHYDROGALACTITOL | DEL MAR PHARMACEUTICALS (CA) | 2014-03-06 | — | — | US | disclosed |
| US-8563758-B2 | Method of synthesis of substituted hexitols such as dianhydrogalactitol | DEL MAR PHARMACEUTICALS (CA) | 2013-10-22 | — | — | US | disclosed |
| US-8563758-B2 | Method of synthesis of substituted hexitols such as dianhydrogalactitol | DEL MAR PHARMACEUTICALS (CA) | 2013-10-22 | — | — | US | disclosed |
| US-20130211111-A1 | METHOD OF SYNTHESIS OF SUBSTISTUTED HEXITOLS SUCH AS DIANHYDROGALACTITOL | DEL MAR PHARMACEUTICALS (CA) | 2013-08-15 | — | — | US | disclosed |
| US-20130211111-A1 | METHOD OF SYNTHESIS OF SUBSTISTUTED HEXITOLS SUCH AS DIANHYDROGALACTITOL | DEL MAR PHARMACEUTICALS (CA) | 2013-08-15 | — | — | US | disclosed |
| WO-2012024368-A2 | METHOD OF SYNTHESIS OF SUBSTITUTED HEXITOLS SUCH AS DIANHYDROGALACTITOL | DEL MAR PHARMACEUTICALS (CA) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155638-A1 | METHOD OF SYNTHESIS OF SUBSTITUTED HEXITOLS SUCH AS DIANHYDROGALACTITOL | DDOST, DAD1, KRTCAP2 | ALDH1A1 1655/4885LMNA 3131/4885L3MBTL1 3157/4885 |
| US-20140066642-A1 | METHOD OF SYNTHESIS OF SUBSTITUTED HEXITOLS SUCH AS DIANHYDROGALACTITOL | DDOST, DAD1, KRTCAP2 | ALDH1A1 1655/4885LMNA 3131/4885L3MBTL1 3157/4885 |
| US-20150329511-A1 | METHOD OF SYNTHESIS OF SUBSTITUTED HEXITOLS SUCH AS DIANHYDROGALACTITOL | DDOST, DAD1, KRTCAP2 | ALDH1A1 1655/4885LMNA 3131/4885L3MBTL1 3157/4885 |
| US-20130211111-A1 | METHOD OF SYNTHESIS OF SUBSTISTUTED HEXITOLS SUCH AS DIANHYDROGALACTITOL | DDOST, DAD1, AGL | ALDH1A1 2795/4885LMNA 1893/4885L3MBTL1 3238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.