Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10048385 | 0.86 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL10047724 | 0.85 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL10048239 | 0.85 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL17339916 | 0.83 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL9983087 | 0.82 | P2RX3 (0.78) | P2RX3 | |
| SCHEMBL10048228 | 0.82 | P2RX3 (0.85) | P2RX3 | |
| SCHEMBL17339915 | 0.82 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL17339917 | 0.82 | P2RX3 (0.89) | P2RX3 | |
| SCHEMBL10055860 | 0.82 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL10047959 | 0.81 | P2RX3 (1.00) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604260-B1 | NOVEL HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | SHIONOGI & CO (JP) | 2017-05-10 | — | — | EP | disclosed |
| US-9212130-B2 | Heterocyclic derivative and pharmaceutical composition comprising the same | SHIONOGI & CO., LTD. (JP) | 2015-12-15 | — | — | US | disclosed |
| US-9212130-B2 | Heterocyclic derivative and pharmaceutical composition comprising the same | SHIONOGI & CO., LTD. (JP) | 2015-12-15 | — | — | US | disclosed |
| WO-2012020742-A1 | NOVEL HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 塩野義製薬株式会社 (JP) | 2012-02-16 | — | — | WO | disclosed |