Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 15/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2724962 | 0.85 | DHODH (0.42) | DHODHMAOBIMPDH2 | |
| SCHEMBL16776537 | 0.84 | DHODH (0.42) | DHODHMAOB | |
| SCHEMBL2730783 | 0.84 | DHODH (0.50) | DHODHMAOB | |
| SCHEMBL3902259 | 0.84 | DHODH (0.42) | DHODHMAOB | |
| SCHEMBL2726180 | 0.83 | DHODH (0.41) | DHODHMAOB | |
| SCHEMBL2724613 | 0.83 | NAAA (0.42) | DHODHMAOB | |
| SCHEMBL2724829 | 0.83 | DHODH (0.41) | DHODHMAOB | |
| SCHEMBL2733653 | 0.83 | NAAA (0.42) | DHODHMAOB | |
| SCHEMBL10048618 | 0.82 | DHODH (0.44) | DHODHMAOB | |
| SCHEMBL2727108 | 0.82 | DHODH (0.42) | IGF1RSRCAXLPTK2AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012060387-A1 | NOVEL DIHYDROXYBENZENE DERIVATIVES AND ANTIPROTOZOAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | アリジェン製薬株式会社 (JP) | 2012-05-10 | — | — | WO | disclosed |