Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.37 |
| ▸ | SQLE | Q14534 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853223 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KMT2AKDM4EATMALOX15 | |
| SCHEMBL9482366 | 0.96 | KMT2A (0.48) | ALDH1A1KMT2AKDM4EALOX15MEN1 | |
| SCHEMBL11652561 | 0.96 | KMT2A (0.48) | ALDH1A1KMT2AKDM4EALOX15MEN1 | |
| SCHEMBL1300611 | 0.82 | KMT2A (0.61) | ALDH1A1KMT2AKDM4EATMALOX15 | |
| SCHEMBL22134472 | 0.82 | KMT2A (0.61) | ALDH1A1KMT2AKDM4EATMALOX15 | |
| SCHEMBL5708634 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KMT2AKDM4EATMALOX15 | |
| SCHEMBL12037686 | 0.82 | KMT2A (0.43) | ALDH1A1KMT2AKDM4EATMALOX15 | |
| SCHEMBL17443890 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KMT2AKDM4EATMALOX15 | |
| SCHEMBL1300612 | 0.82 | KMT2A (0.61) | ALDH1A1KMT2AKDM4EATMALOX15 | |
| SCHEMBL10323577 | 0.82 | KMT2A (0.61) | ALDH1A1KMT2AKDM4EATMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012060387-A1 | NOVEL DIHYDROXYBENZENE DERIVATIVES AND ANTIPROTOZOAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | アリジェン製薬株式会社 (JP) | 2012-05-10 | — | — | WO | disclosed |
| US-4105697-A | Process for the preparation of α, β-ethylenic aldehydes | RHONE-POULENC INDUSTRIES (FR) | 1978-08-08 | — | — | US | disclosed |