SCHEMBL10049013

SCHEMBL10049013

CC1(C)CC2(CC(C)(C)c3ccc(Nc4ccc(-c5ccccc5)cc4)cc32)c2cc(Nc3ccc(-c4ccccc4)cc3)ccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.37
RARG P13631 4/20 0.37
RARA P10276 3/20 0.37
ALDH1A1 P00352 4/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPT P10636 2/20 0.36
AR P10275 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
HSD17B10 Q99714 3/20 0.35
ALOX15 P16050 2/20 0.35
ALOX12 P18054 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TSHR P16473 1/20 0.35
PTGS1 P23219 1/20 0.35
SLC6A2 P23975 1/20 0.35
MAPK1 P28482 1/20 0.35
PTGS2 P35354 1/20 0.35
HTR2B P41595 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26306922 0.91 RARB (0.41) RARBRARGRARAALDH1A1MEN1
SCHEMBL10050587 0.85 GAA (0.39) RARBRARGRARAALDH1A1MAPT
SCHEMBL27395133 0.84 RARB (0.51) RARBRARGRARAALDH1A1MEN1
SCHEMBL26306086 0.84 RARB (0.48) RARBRARGRARAALDH1A1MEN1
SCHEMBL31375685 0.84 RARB (0.51) RARBRARGRARAALDH1A1MEN1
SCHEMBL25491015 0.84 RARB (0.51) RARBRARGRARAALDH1A1MEN1
SCHEMBL17449894 0.79 RARA (0.34) RARBRARGRARA
SCHEMBL25491121 0.78 RARA (0.58) RARBRARGRARAALDH1A1MEN1
SCHEMBL27395129 0.77 RARB (0.57) RARBRARGRARAALDH1A1MEN1
SCHEMBL22180771 0.76 RARB (0.41) RARBRARGRARAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9685613-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2017-06-20 US disclosed
US-9685613-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2017-06-20 US disclosed
US-20130248848-A1 PROCESS AND MATERIALS FOR MAKING CONTAINED LAYERS AND DEVICES MADE WITH SAME E.I. DU PONT NEMOURS AND COMPANY (US) 2013-09-26 US disclosed
US-20130248848-A1 PROCESS AND MATERIALS FOR MAKING CONTAINED LAYERS AND DEVICES MADE WITH SAME E.I. DU PONT NEMOURS AND COMPANY (US) 2013-09-26 US disclosed
US-20130248847-A1 ELECTROACTIVE MATERIALS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-09-26 US disclosed
US-20130248847-A1 ELECTROACTIVE MATERIALS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-09-26 US disclosed
WO-2012087977-A1 PROCESS AND MATERIALS FOR MAKING CONTAINED LAYERS AND DEVICES MADE WITH SAME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-28 WO disclosed
WO-2012087930-A2 ELECTROACTIVE MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-28 WO disclosed