Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 2/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.58 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.58 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.58 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.58 |
| ▸ | LTK | P29376 | 1/20 | 0.50 |
| ▸ | MST1R | Q04912 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 3/20 | 0.42 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26928872 | 0.81 | CDK5 (0.53) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL29532218 | 0.75 | PARP1 (0.70) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL6297545 | 0.75 | PARP1 (0.70) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL9475196 | 0.73 | PARP1 (0.68) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL1078443 | 0.73 | CDK5 (0.61) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL24142865 | 0.73 | CDK5 (0.61) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL31303452 | 0.73 | CDK5 (0.61) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL2379452 | 0.73 | CDK5 (0.61) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL867264 | 0.73 | PARP1 (0.68) | CDK5DYRK1ACLK4PIM1CSNK1A1 | |
| SCHEMBL24148319 | 0.73 | CDK5 (0.61) | CDK5DYRK1ACLK4PIM1CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |