⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL1557458 | 0.84 | HTT (0.35) | — | |
| SCHEMBL31324642 | 0.77 | — | — | |
| SCHEMBL1868904 | 0.77 | — | — | |
| SCHEMBL5000 | 0.73 | — | — | |
| SCHEMBL64291 | 0.72 | — | — | |
| SCHEMBL37679 | 0.72 | — | — | |
| SCHEMBL10352959 | 0.72 | — | — | |
| SCHEMBL31693851 | 0.72 | — | — | |
| SCHEMBL9574887 | 0.72 | — | — | |
| Bromide SCHEMBL11152275 | 0.70 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622334-A | Synthetic method of 3-bromo-9,9'-spirobifluorene | INST OF CHEMISTRY CO LTD HENAN ACAD OF SCIENCES | 2016-06-01 | — | — | CN | claimed |
| US-6458962-B1 | VIRICIDES FOR TREATMENT OF AIDS AND HYDROGENATION OF COMPOUNDS | THE UNIVERSITY OF TENNESSEEE RESEARCH CORPORATION | 2002-10-01 | — | — | US | claimed |
| WO-2000056332-A1 | SULTAMS: CATALYST SYSTEMS FOR ASYMMETRIC REDUCTION OF A C=N INTERMEDIATE BIOLOGICAL COMPOSITIONS AND METHODS FOR MAKING THE SULTAMS | THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) | 2000-09-28 | — | — | WO | claimed |
| JP-5255331-A | — | — | None | — | — | JP | disclosed |
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| WO-2024200777-A1 | SUBSTITUTED HYDROXYMETHYL PYRROLIDINES FOR USE IN THE TREATMENT OF HYPERGLYCAEMIA AND DISORDERS CHARACTERISED BY HYPERGLYCAEMIA | ATROGI AB (SE) | 2024-10-03 | — | — | WO | disclosed |
| CN-111372932-B | Novel benzylamino-substituted pyridopyrimidinones and derivatives as SOS1 inhibitors | 勃林格殷格翰国际有限公司 | 2023-11-21 | — | — | CN | disclosed |
| US-11814380-B2 | Benzylamino substituted pyridopyrimidinones and derivatives as SOS1 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-11-14 | — | — | US | disclosed |
| US-20230293522-A1 | HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-09-21 | — | — | US | disclosed |
| EP-4219493-A1 | BENZYLAMINO SUBSTITUTED PYRIDOPYRIMIDINONES AND DERIVATIVES AS SOS1 INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2023-08-02 | — | — | EP | disclosed |
| US-5334590-A | MRSA active 2-phenyl-carbapenems | MERCK & CO., INC. (US) | 1994-08-02 | — | — | US | disclosed |
| US-5256777-A | Bactericides | MERCK & CO., INC. (US) | 1993-10-26 | — | — | US | disclosed |
| JP-H05255331-A | MRSA ACTIVE 2-HALOPHENYLCARBAPENEM | MERCK & CO INC | 1993-10-05 | — | — | JP | disclosed |
| EP-0538016-A1 | MRSA active 2-phenyl-carbapenems | MERCK & CO. INC. (US) | 1993-04-21 | — | — | EP | disclosed |
| EP-0538001-A1 | MRSA active 2-halophenyl carbapenems | MERCK & CO. INC. (US) | 1993-04-21 | — | — | EP | disclosed |
| EP-0024943-B1 | 5,6,7-TRINOR-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | TORAY INDUSTRIES, INC. (JP) | 1983-08-17 | — | — | EP | disclosed |
| US-4301164-A | FOR USE AS ANTIULCER AGENTS, HYPOTENSIVE AGENTS, ANTITHROMBOSIC AGENTS | TORAY INDUSTRIES, INC. (JP) | 1981-11-17 | — | — | US | disclosed |
| EP-0024943-A1 | 5,6,7-Trinor-4,8-inter-m-phenylene PGI2 derivatives and pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1981-03-11 | — | — | EP | disclosed |
| US-3974143-A | (16α)-16,17-ALKYLIDENEBIS(OXY)-3-ARYLPREGNA-2,4-TRIEN-20-ONES | G. D. SEARLE & CO. (US) | 1976-08-10 | — | — | US | disclosed |