Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926390 | 0.82 | — | — | |
| SCHEMBL12360370 | 0.81 | NPC1 (0.36) | NPC1 | |
| SCHEMBL5754557 | 0.80 | NPC1 (0.52) | NPC1 | |
| SCHEMBL15397400 | 0.79 | NPC1 (0.35) | NPC1 | |
| SCHEMBL9275152 | 0.79 | NPC1 (0.35) | NPC1 | |
| SCHEMBL23571323 | 0.79 | NPC1 (0.35) | NPC1 | |
| SCHEMBL15305930 | 0.79 | NPC1 (0.35) | NPC1 | |
| SCHEMBL24994506 | 0.79 | NPC1 (0.35) | NPC1 | |
| SCHEMBL10049953 | 0.79 | NPC1 (0.35) | NPC1 | |
| SCHEMBL15305934 | 0.79 | NPC1 (0.35) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595967-B1 | TETRAZINE-TRANS-CYCLOOCTENE LIGATION FOR THE RAPID CONSTRUCTION OF RADIONUCLIDE LABELED PROBES | UNIV DELAWARE (US) | 2016-03-23 | — | — | EP | disclosed |
| US-20130266512-A1 | Tetrazine-trans-cyclooctene Ligation for the Rapid Construction of Radionuclide Labeled Probes | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-10-10 | — | — | US | disclosed |
| US-20130266512-A1 | Tetrazine-trans-cyclooctene Ligation for the Rapid Construction of Radionuclide Labeled Probes | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-10-10 | — | — | US | disclosed |
| WO-2012012612-A2 | TETRAZINE-TRANS-CYCLOOCTENE LIGATION FOR THE RAPID CONSTRUCTION OF RADIONUCLIDE LABELED PROBES | UNIVERSITY OF DELAWARE (US) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130266512-A1 | Tetrazine-trans-cyclooctene Ligation for the Rapid Construction of Radionuclide Labeled Probes | TTL, TALDO1, TTI1 | NPC1 3606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.