Sugi Predict
/ Targets
/ TTI1
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours |
|---|
Clinical trials — most relevant to TTI1 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| Nandrolone Decanoate in the Treatment of Telomeropathies |
PHASE1/PHASE2 | COMPLETED |
| A Phase I/II, First-In-Human Trial to Evaluate the Safety, Tolerability, and Pharmacokinetic Activity to Prevent or Treat Neuropsychiatric Symptoms in Pediatric Subjects With Timothy Syndrome |
PHASE1/PHASE2 | NOT_YET_RECRUITING |
| Danazol for Genetic Bone Marrow and Lung Disorders |
PHASE1/PHASE2 | COMPLETED |
| Gene-Modified Stem Cell Therapy for Children With Autosomal Recessive Osteopetrosis (ARO) |
PHASE1/PHASE2 | RECRUITING |
| TTFields and Chemotherapy in Metastatic Pancreatic Adenocarcinoma (mPDAC) |
PHASE1/PHASE2 | RECRUITING |
| PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS |
PHASE2 | COMPLETED |
| Imetelstat for Children With Refractory or Recurrent Solid Tumors and Lymphoma |
PHASE1 | WITHDRAWN |
| Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors |
PHASE1 | COMPLETED |
| Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants |
nan | RECRUITING |
| Telomere Repair Gene Mutation in Inflammatory Bowel Disease |
nan | COMPLETED |
| The Impact of Mitochondrial Dysfunction on Human Bone Cell Metabolism and Remodelling |
nan | ACTIVE_NOT_RECRUITING |
| Telomere Disclosure and Impact on Psychological Distress and Health Behaviors |
nan | COMPLETED |
| Telomeres Length in Israeli Fibrotic ILD Patients |
nan | ENROLLING_BY_INVITATION |
| Nasal Brushing for the Diagnosis and Understanding of Telomeropathies |
nan | UNKNOWN |
| Treatment of Chronic Lymphocytic Leukemia |
nan | UNKNOWN |
| Biological Aging Hallmarks-Guided Integrative TCM and Conventional Medicine in Post-Treatment Unexplained Female Infertility |
nan | RECRUITING |
| Improvement of DIAgnostic and Phenotype-genotype Correlation Studies in Patients With MYOpathy Suspected of TITinopathy |
nan | UNKNOWN |
| A Study Of Deep Learning For Echo Analysis, Tracking, And Evaluation |
nan | RECRUITING |
| Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) |
nan | COMPLETED |
| Autophagy in Systemic Lupus Erythematosus |
nan | UNKNOWN |
| Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome |
nan | RECRUITING |
| Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm |
nan | COMPLETED |
| Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome |
nan | RECRUITING |
| Telomere and Telomerase |
nan | WITHDRAWN |
| Impact of Bariatric and Metabolic Surgery on the Reduction of Premature Aging. |
nan | COMPLETED |
| Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics |
nan | UNKNOWN |
| Study on Genetically Affected Sporadic Thoracic Aortic Aneurysm and Dissection |
nan | COMPLETED |
| Telomeric Abnormalities in Colorectal Diseases by Fluorescent in Situ Hybridization Technique |
nan | UNKNOWN |
| Body Awareness and Aerobic Exercise: Telomere Impact |
nan | COMPLETED |
| Assessment Of Long Noncoding RNA CCAT1 In Colorectal Cancer Patients |
nan | UNKNOWN |
Related proteins — ESM-2 sequence neighbours (a TTI1 binder may also engage these)