SCHEMBL10049883

SCHEMBL10049883

C=CCOC(=O)NCCC(C)(C)C(=O)SCCOP(OC1C(COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)OC(n2ccc(NC(=O)COc3ccccc3)nc2=O)C1F)N(C(C)C)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TYMP P19971 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10049877 0.95 TYMP (0.32) TYMP
SCHEMBL10049882 0.93 TYMP (0.34) TYMP
SCHEMBL18787582 0.87 TYMP (0.36) TYMP
SCHEMBL10049844 0.87 TYMP (0.34) TYMP
SCHEMBL10049987 0.87 TYMP (0.32) TYMP
SCHEMBL10049739 0.83 TYMP (0.35) TYMP
SCHEMBL10050040 0.83 TYMP (0.36) TYMP
SCHEMBL4339161 0.83 TYMP (0.37) TYMP
SCHEMBL4345631 0.82 TYMP (0.36) TYMP
SCHEMBL10049841 0.82 TYMP (0.33) TYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120142763-A1 NUCLEIC ACID DELIVERY COMPOSITIONS AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-06-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142763-A1 NUCLEIC ACID DELIVERY COMPOSITIONS AND METHODS OF USE THEREOF NSUN3, NSUN2, DIS3 TYMP 152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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