SCHEMBL10050306

SCHEMBL10050306

C=C1CC(=O)N(C(C)C(N)=O)C1=O

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 3/20 0.38
HTT P42858 1/20 0.38
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA13 Q8N1Q1 1/20 0.30
CA14 Q9ULX7 1/20 0.30
CA5B Q9Y2D0 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10037952 0.79 POLB (0.33) MAPT
SCHEMBL10037949 0.76 SLC1A2 (0.40) KMT2AHTTMAPT
SCHEMBL10037963 0.74 POLB (0.33) MAPT
SCHEMBL9182487 0.72 KMT2A (0.49) MEN1KMT2ALMNAHTTCA12
SCHEMBL7106786 0.67 KDM4E (0.32) MEN1KMT2AMAPT
SCHEMBL2347972 0.65 KMT2A (0.49) MEN1KMT2ALMNAHTTMAPT
SCHEMBL27253677 0.65 KMT2A (0.49) MEN1KMT2ALMNAHTTMAPT
SCHEMBL659939 0.64 PDE5A (0.49) MEN1KMT2ALMNAHTTMAPT
SCHEMBL22728344 0.63 NOTUM (0.43)
SCHEMBL10434423 0.63 MEN1 (0.44) MEN1KMT2ALMNAHTTCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8158746-B2 Active energy ray curable liquid composition and liquid cartridge CANON KABUSHIKI KAISHA (JP) 2012-04-17 US disclosed
US-20100324163-A1 ACTIVE ENERGY RAY CURABLE LIQUID COMPOSITION AND LIQUID CARTRIDGE CANON KABUSHIKI KAISHA (JP) 2010-12-23 US disclosed