SCHEMBL10037952

SCHEMBL10037952

C=C1CC(=O)N(C(C)C(=O)NC(C)N)C1=O

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.32
SLC1A2 P43004 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10037963 0.84 POLB (0.33) POLBMAPTSLC1A2
SCHEMBL10037953 0.80 SLC1A2 (0.30) SLC1A2
SCHEMBL10050306 0.79 MEN1 (0.41) MAPT
SCHEMBL10037954 0.76 SLC1A2 (0.34) SLC1A2
SCHEMBL10037576 0.75
SCHEMBL4903842 0.70 GAA (0.33) GAA
SCHEMBL10037551 0.70 POLB (0.38) POLBMAPTSLC1A2
SCHEMBL10037554 0.68 POLB (0.37) POLBMAPT
SCHEMBL10770312 0.59
SCHEMBL25966356 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124791-B2 Active energy ray curable liquid composition and liquid cartridge CANON KABUSHIKI KAISHA (JP) 2012-02-28 US disclosed
US-20100094024-A1 ACTIVE ENERGY RAY CURABLE LIQUID COMPOSITION AND LIQUID CARTRIDGE CANON KABUSHIKI KAISHA (JP) 2010-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100094024-A1 ACTIVE ENERGY RAY CURABLE LIQUID COMPOSITION AND LIQUID CARTRIDGE C9, MLX, CHRM1 POLB 207/4885MAPT 1636/4885SLC1A2 933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.