Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | BRS3 | P32247 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10050458 | 0.95 | ATR (0.40) | ATRMAOBPARP1PARP2AR | |
| SCHEMBL10050443 | 0.86 | MAOB (0.37) | ATRMAOBPARP1TGFBR1CDK5 | |
| SCHEMBL10074516 | 0.84 | ATR (0.44) | ATRMAOBPARP1PARP2AR | |
| SCHEMBL10050435 | 0.84 | MAOB (0.38) | MAOBARIDO1ALDH1A3PDK2 | |
| SCHEMBL10050448 | 0.84 | MAPT (0.34) | ATRMAOBALDH1A3 | |
| SCHEMBL10050444 | 0.81 | MAOB (0.37) | ATRMAOBPARP1TGFBR1 | |
| SCHEMBL10074510 | 0.80 | ATR (0.44) | ATRMAOBPARP1PARP2AR | |
| SCHEMBL10050462 | 0.79 | PDK2 (0.37) | MAOBGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10050446 | 0.77 | ATR (0.36) | ATRMAOB | |
| SCHEMBL10050412 | 0.77 | ATR (0.42) | ATRMAOBPARP1PARP2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119828-B2 | Material for an organic electroluminescence device and an organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20100044686-A1 | MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100044686-A1 | MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND AN ORGANIC ELECTROLUMINESCENCE DEVICE | AFF4, KCNH3, HCN4 | ATR 2855/4885MAOB 1019/4885PARP1 2672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.