Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16379449 | 0.96 | THRB (0.61) | THRBMAPTRAB9APKMPARP10 | |
| SCHEMBL18200239 | 0.94 | THRB (0.57) | THRBMAPTRAB9APARP10MMP3 | |
| SCHEMBL14130742 | 0.94 | THRB (0.57) | THRBMAPTRAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL16379460 | 0.94 | THRB (0.57) | THRBMAPTRAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL16379469 | 0.94 | THRB (0.57) | THRBMAPTRAB9APARP10MMP3 | |
| SCHEMBL16379492 | 0.93 | THRB (0.56) | THRBSMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL16379455 | 0.93 | THRB (0.56) | THRBSMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL12604142 | 0.93 | THRB (0.56) | THRBSMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL23943770 | 0.91 | THRB (0.56) | THRBMAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL17301210 | 0.91 | THRB (0.56) | THRBMAPTSMN1; SMN2TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1990339-B1 | DIOXETANE COMPOUND, CATIONICALLY POLYMERIZABLE COMPOSITION, OPTICAL FILM AND LIQUID CRYSTAL DISPLAY UNIT | NIPPON OIL CORP (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-7998543-B2 | Dioxetane compound, cationically polymerizable composition, optical film, and liquid crystal display device | NIPPON OIL CORPORATION (JP) | 2011-08-16 | — | — | US | disclosed |
| US-7998543-B2 | Dioxetane compound, cationically polymerizable composition, optical film, and liquid crystal display device | NIPPON OIL CORPORATION (JP) | 2011-08-16 | — | — | US | disclosed |
| US-7763182-B2 | Liquid crystalline composition with improved adhesivity, liquid crystal film comprising the composition, and liquid crystal display device equipped with the film | NIPPON OIL CORPORATION (JP) | 2010-07-27 | — | — | US | disclosed |
| US-7763182-B2 | Liquid crystalline composition with improved adhesivity, liquid crystal film comprising the composition, and liquid crystal display device equipped with the film | NIPPON OIL CORPORATION (JP) | 2010-07-27 | — | — | US | disclosed |
| US-20090208673-A1 | Liquid Crystalline Composition with Improved Adhesivity, Liquid Crystal Film Comprising the Composition, and Liquid Crystal Display Device Equipped with the Film | NIPPON OIL CORPORATION (JP) | 2009-08-20 | — | — | US | disclosed |
| US-20090208673-A1 | Liquid Crystalline Composition with Improved Adhesivity, Liquid Crystal Film Comprising the Composition, and Liquid Crystal Display Device Equipped with the Film | NIPPON OIL CORPORATION (JP) | 2009-08-20 | — | — | US | disclosed |
| US-20090068379-A1 | DIOXETANE COMPOUND, CATIONICALLY POLYMERIZABLE COMPOSITION, OPTICAL FILM, AND LIQUID CRYSTAL DISPLAY DEVICE | NIPPON OIL CORPORATION (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20090068379-A1 | DIOXETANE COMPOUND, CATIONICALLY POLYMERIZABLE COMPOSITION, OPTICAL FILM, AND LIQUID CRYSTAL DISPLAY DEVICE | NIPPON OIL CORPORATION (JP) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090068379-A1 | DIOXETANE COMPOUND, CATIONICALLY POLYMERIZABLE COMPOSITION, OPTICAL FILM, AND LIQUID CRYSTAL DISPLAY DEVICE | OCIAD1, OCIAD2, DAXX | THRB 4420/4885MAPT 473/4885RAB9A 1866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.