⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9910065 | 0.85 | — | — | |
| SCHEMBL18134378 | 0.69 | HTR2C (0.31) | — | |
| SCHEMBL761153 | 0.65 | TSHR (0.39) | — | |
| SCHEMBL22433110 | 0.65 | — | — | |
| SCHEMBL21955629 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL25342137 | 0.59 | BLM (0.41) | — | |
| SCHEMBL9912449 | 0.58 | — | — | |
| SCHEMBL10050831 | 0.58 | — | — | |
| SCHEMBL30037332 | 0.57 | — | — | |
| SCHEMBL24960299 | 0.55 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807626-B2 | Compounds and methods for CD73 modulation and indications therefor | Opna Bio SA (CH) | 2023-11-07 | — | — | US | disclosed |
| US-20210340121-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2021-11-04 | — | — | US | disclosed |
| US-20170135926-A1 | TOPICAL COMPOSITIONS AND METHODS FOR SKIN LIGHTENING | AVON PROD INC (US) | 2017-05-18 | — | — | US | disclosed |
| US-9592186-B2 | Topical compositions and methods for skin lightening | AVON PRODUCTS, INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-9566224-B2 | Tyrosinase inhibitors | AVON PRODUCTS, INC. (US) | 2017-02-14 | — | — | US | disclosed |
| US-9364405-B2 | Tyrosinase inhibitors | AVON PRODUCTS, INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-20150202146-A1 | Paxillin Stimulating Compositions and Cosmetic Uses Thereof | AVON PRODUCTS, INC. | 2015-07-23 | — | — | US | disclosed |
| US-9066896-B2 | Paxillin stimulating compositions and cosmetic uses thereof | AVON PRODUCTS, INC. (US) | 2015-06-30 | — | — | US | disclosed |
| US-20150174034-A1 | TYROSINASE INHIBITORS | AVON PRODUCTS, INC. | 2015-06-25 | — | — | US | disclosed |
| US-20150164758-A1 | TYROSINASE INHIBITORS | CITIBANK, N.A., LONDON BRANCH | 2015-06-18 | — | — | US | disclosed |
| US-20150118170-A1 | TYROSINASE INHIBITORS | AVON PRODUCTS, INC. | 2015-04-30 | — | — | US | disclosed |
| US-8394427-B2 | Paxillin stimulating compositions and cosmetic uses thereof | AVON PRODUCTS, INC. (US) | 2013-03-12 | — | — | US | disclosed |
| US-20120328546-A1 | Paxillin Stimulating Compositions and Cosmetic Uses Thereof | AVON PRODUCTS, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| US-8168212-B2 | Topical compositions comprising non-proteogenic amino acids and methods of treating skin | AVON PRODUCTS, INC (US) | 2012-05-01 | — | — | US | disclosed |
| US-20110151029-A1 | Paxillin Stimulating Compositions and Cosmetic Uses Thereof | AVON PRODUCTS, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| US-20100261769-A1 | Topical Compositions Comprising Non-Proteogenic Amino Acids and Methods of Treating Skin | AVON PRODUCTS, INC. (US) | 2010-10-14 | — | — | US | disclosed |