SCHEMBL10051144

SCHEMBL10051144

CCC1(COCCCCOc2ccc(C)cc2)COC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 6/20 0.41
DRD4 P21917 6/20 0.41
DRD3 P35462 6/20 0.41
KDM4E B2RXH2 1/20 0.40
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
KCNH2 Q12809 2/20 0.36
MAPK1 P28482 2/20 0.36
ABCB11 O95342 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
ALDH1A1 P00352 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
HTR2A P28223 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12200958 0.99 KDM4E (0.40) DRD2DRD4DRD3KDM4ECYP1A2
SCHEMBL12619857 0.90 KDM4E (0.34) DRD2DRD4DRD3KDM4ECYP1A2
SCHEMBL12974363 0.86 HRH2 (0.38) KMT2ALMNA
SCHEMBL12199819 0.86 LMNA (0.46) CYP1A2CYP3A4CYP2C9CYP2C19MEN1
SCHEMBL5423169 0.86 KDM4E (0.42) DRD2DRD4DRD3KDM4EL3MBTL1
SCHEMBL12200938 0.86 KDM4E (0.42) DRD2DRD4DRD3KDM4EL3MBTL1
SCHEMBL14075165 0.86 RARB (0.39) DRD2DRD4DRD3KDM4ECYP1A2
SCHEMBL1127852 0.85 TSHR (0.39) DRD2DRD4DRD3CYP1A2CYP3A4
SCHEMBL16214197 0.84 GBA1 (0.37) MEN1KMT2AL3MBTL1KCNH2LMNA
SCHEMBL10170084 0.84 KCNA3 (0.43) DRD2DRD4DRD3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2404763-A2 Counterfeiting prevention device having printing and birefringence pattern Fujifilm Corporation (JP) 2012-01-11 EP disclosed
US-7393569-B2 Hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyl acrylates); hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyloxetanes; stabilizes polymerizable liquid crystal compositions for a long time and controls the alignment of liquid crystal molecules CHISSO CORPORATION (JP) 2008-07-01 US disclosed
US-7393569-B2 Hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyl acrylates); hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyloxetanes; stabilizes polymerizable liquid crystal compositions for a long time and controls the alignment of liquid crystal molecules CHISSO CORPORATION (JP) 2008-07-01 US disclosed