SCHEMBL10051744

SCHEMBL10051744

C=C=NC(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL521487 0.72
SCHEMBL6142998 0.72
SCHEMBL3409565 0.67
SCHEMBL13180582 0.65
SCHEMBL8169705 0.64
Hydrochloric Acid SCHEMBL1353085 0.64 TRPA1 (0.47)
Bromide SCHEMBL10663202 0.64 TRPA1 (0.47)
SCHEMBL78328 0.61
Isopropyl Isothiocyanate SCHEMBL213474 0.61
SCHEMBL31414859 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11913071-B2 Methods and compositions for sequencing complementary polynucleotides Singular Genomics Systems, Inc. (US) 2024-02-27 US disclosed
US-20230399692-A1 NUCLEIC ACID DELIVERY SCAFFOLDS FIRST-CITIZENS BANK & TRUST COMPANY 2023-12-14 US disclosed
US-20230357828-A1 SPATIAL SEQUENCING OF MODIFIED SEQUENCES FIRST-CITIZENS BANK & TRUST COMPANY 2023-11-09 US disclosed
US-11795505-B2 Nucleic acid delivery scaffolds Singular Genomics Systems, Inc. (US) 2023-10-24 US disclosed
US-11788080-B2 Modified cleavases, uses thereof and related kits Encodia, Inc. (US) 2023-10-17 US disclosed
US-11788133-B2 Methods and compositions for sequencing complementary polynucleotides Singular Genomics Systems, Inc. (US) 2023-10-17 US disclosed
US-11782062-B2 Kits for analysis using nucleic acid encoding and/or label Encodia, Inc. (US) 2023-10-10 US disclosed
US-20230295437-A1 SILICON CONTAINING DETECTABLE COMPOUNDS Singular Genomics Systems, Inc. 2023-09-21 US disclosed
US-20230287491-A1 NUCLEIC ACID DELIVERY SCAFFOLDS FIRST-CITIZENS BANK & TRUST COMPANY 2023-09-14 US disclosed
US-11753678-B2 Spatial sequencing Singular Genomics Systems, Inc. (US) 2023-09-12 US disclosed
US-11643679-B2 Methods for in situ transcriptomics and proteomics SINGULAR GENOMICS SYTEMS, INC. (US) 2023-05-09 US disclosed
US-20160130299-A1 TUBULYSIN ANALOGS AND METHODS OF MAKING AND USE BRISTOL-MYERS SQUIBB COMPANY 2016-05-12 US disclosed
US-20150175998-A1 Methods and Kits to Create Protein Substrate˜HECT-Ubiquitin Ligase Pairs NORTHWESTERN UNIVERSITY 2015-06-25 US disclosed
US-8772542-B2 Antiproliferative compounds, conjugates thereof, methods therefor, and uses thereof MEDAREX, L.L.C. (US) 2014-07-08 US disclosed
US-20130197259-A1 ANTIPROLIFERATIVE COMPOUNDS, CONJUGATES THEREOF, METHODS THEREFOR, AND USES THEREOF MEDAREX, INC. (US) 2013-08-01 US disclosed
US-8420084-B2 Fully human antibodies specific to CADM1 MEDAREX, INC. (US) 2013-04-16 US disclosed
US-20120093826-A1 FULLY HUMAN ANTIBODIES SPECIFIC TO CADM1 OXFORD BIOTHERAPEUTICS LTD (GB) 2012-04-19 US disclosed
US-20110178281-A1 Photocleavable Linker Methods and Compositions THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2011-07-21 US disclosed
US-7923562-B2 Photocleavable linker methods and compositions THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2011-04-12 US disclosed
US-20100022761-A1 PHOTOCLEAVABLE LINKER METHODS AND COMPOSITIONS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2010-01-28 US disclosed