Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099981 | 1.00 | TSHR (0.45) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL8077217 | 0.91 | LMNA (0.43) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL5398466 | 0.91 | LMNA (0.43) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL428372 | 0.91 | LMNA (0.43) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL554360 | 0.91 | LMNA (0.43) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| 1,6-Hexanediol SCHEMBL15347446 | 0.91 | LMNA (0.43) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL13202549 | 0.91 | LMNA (0.43) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL10406986 | 0.91 | LMNA (0.43) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL830579 | 0.91 | LMNA (0.43) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL19411359 | 0.91 | LMNA (0.43) | TSHRALDH1A1LMNAHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011675-A1 | PHARMACEUTICALLY ACCEPTABLE FORMULATIONS/COMPOSITIONS FOR PEPTIDYL DRUGS | ZELOS THERAPEUTICS, INC. (US) | 2011-01-27 | — | — | WO | claimed |
| US-20140357806-A1 | THERMAL-RESPONSIVE POLYMER NETWORKS, COMPOSITIONS, AND METHODS AND APPLICATIONS RELATED THERETO | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL (US) | 2014-12-04 | — | — | US | disclosed |
| WO-2011011675-A1 | PHARMACEUTICALLY ACCEPTABLE FORMULATIONS/COMPOSITIONS FOR PEPTIDYL DRUGS | ZELOS THERAPEUTICS, INC. (US) | 2011-01-27 | — | — | WO | disclosed |
| WO-2002051395-A1 | TREATMENT OF NEURODEGENERATIVE DISEASES | CODON PHARMACEUTICALS, INC. (US) | 2002-07-04 | — | — | WO | disclosed |
| US-4505981-A | Heat-hardenable binder mixture | BASF FARBEN & FASERN AG (DE) | 1985-03-19 | — | — | US | disclosed |